ID A0A2P1NIA3_9BURK Unreviewed; 380 AA.
AC A0A2P1NIA3;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Mechanosensitive ion channel protein MscS {ECO:0000313|EMBL:AVP56710.1};
GN ORFNames=C7H73_02775 {ECO:0000313|EMBL:AVP56710.1};
OS Pulveribacter suum.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Pulveribacter.
OX NCBI_TaxID=2116657 {ECO:0000313|EMBL:AVP56710.1, ECO:0000313|Proteomes:UP000241829};
RN [1] {ECO:0000313|Proteomes:UP000241829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2-7 {ECO:0000313|Proteomes:UP000241829};
RA Kim S.-J., Heo J., Ahn J.-H., Kwon S.-W.;
RT "Genome sequencing of Melaminivora sp. strain SC2-7.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP027792; AVP56710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P1NIA3; -.
DR KEGG; melm:C7H73_02775; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000241829; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000241829};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 148..187
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 188..254
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 261..340
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 380 AA; 40648 MW; 666FE98DAC7DBEE2 CRC64;
MEFAQDWPWL HREAFGGMSA ASVLLAVAAA MGTYLLLTLL LRWAQRRARR HDEGVGKPGA
SGLLAQLLAG TSHLLIVLAA VLVGLGLLDL PQRWHGRVGQ LWFLAVAVQI GLWGSRAIGV
AVQRYRQHHG STSAGQAGAS ATLMSWGLRT VLWVTVLLAI LSNLGVNITA FVASLGVGGV
AVALAVQNIL GDLFASMAIA VDKPFEVGDF IVVNGVAGTV QKVGVKTTRI KALSGEQVVM
GNTDLLKQTI NNYRLMRERR IVFTFSIAQA TPVDKVGQVS AVVAEVVKAI PKVRFDRAHF
KAFGASSLDY EVVYIVQDPD FNLYMDIQQR INLQLLERLR TLDVQLAVPV SRLQFNGPPA
DVPPAGALAQ AGAQAGPAQA
//
