ID A0A2P2BMM6_9FIRM Unreviewed; 521 AA.
AC A0A2P2BMM6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN ORFNames=FRIFI_0105 {ECO:0000313|EMBL:CEI71659.1};
OS Romboutsia hominis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Romboutsia.
OX NCBI_TaxID=1507512 {ECO:0000313|EMBL:CEI71659.1, ECO:0000313|Proteomes:UP000245695};
RN [1] {ECO:0000313|EMBL:CEI71659.1, ECO:0000313|Proteomes:UP000245695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRIFI {ECO:0000313|EMBL:CEI71659.1,
RC ECO:0000313|Proteomes:UP000245695};
RA Hornung B.V.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR EMBL; LN650648; CEI71659.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P2BMM6; -.
DR Proteomes; UP000245695; Chromosome Chromosome1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR CDD; cd10333; LeuT-like_sbd; 1.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR NCBIfam; NF037979; Na_transp; 1.
DR PANTHER; PTHR42948; TRANSPORTER; 1.
DR PANTHER; PTHR42948:SF1; TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 2.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245695};
KW Symport {ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 521 AA; 57012 MW; 87E9F9CC81D67D98 CRC64;
MSESRENWGS KVGLILAMAG NAVGLGNFWR FPYVAASNGG GAFMIPYFFA LIVIGIPIML
VEWSIGRHGG KYGHGTIGPM MYLQAKQAMA PKKAIIVGAL CGMIAFGVTI LVNSYYNHII
GWSLGFAFNS LTGGYNSDPG AFFGSYIQDP KNLIFWVISL LCLAFAVMKG IQKGIESWAK
VMMPTLYVFG IILGIRALTL GAPVNPDWSS LAGLNFIWNP DFSQLSWSSA IAAAGQIFFT
LSLGMGIIHN YASYLKPDED IVTASVATVS LNEFAEVILG GTAVIPIAYA FLGPEGIKGS
IGLAFMVLPN VFSTMTGGGI FGALWFLLLF FAGITSAIAM YNYLVALLEE DAGIDRKKGA
WIVFVGYLIV GAPIALESIL TQSANLVYFT EIDNWIGNYL LIVLGLIEII VIGWCVKDKA
LQEMNRGGLW KVPKWFFRLF HQFLTPITII TFLVFFTRDY WMAGNFKITP SYIEGIPEFA
VWVNLGRAVV FGVLLIGFIQ SYKSIKSKYK EEIESNKVTT S
//
