ID A0A2P2E4W6_9LEPT Unreviewed; 556 AA.
AC A0A2P2E4W6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=von Willebrand factor type A domain protein {ECO:0000313|EMBL:GBF51920.1};
GN ORFNames=LPTSP4_34580 {ECO:0000313|EMBL:GBF51920.1};
OS Leptospira ryugenii.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1917863 {ECO:0000313|EMBL:GBF51920.1, ECO:0000313|Proteomes:UP000245133};
RN [1] {ECO:0000313|EMBL:GBF51920.1, ECO:0000313|Proteomes:UP000245133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YH101 {ECO:0000313|EMBL:GBF51920.1,
RC ECO:0000313|Proteomes:UP000245133};
RA Nakao R., Masuzawa T.;
RT "Novel Leptospira species isolated from soil and water in Japan.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBF51920.1}.
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DR EMBL; BFBB01000009; GBF51920.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P2E4W6; -.
DR OrthoDB; 9807628at2; -.
DR Proteomes; UP000245133; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22550:SF5; LEUCINE ZIPPER PROTEIN 4; 1.
DR PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00028; TPR; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS50293; TPR_REGION; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245133};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 90..272
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REPEAT 436..469
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 481..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 63223 MW; 5C962C79B624E264 CRC64;
METFVSVKIL GILAISLFAF LFFGKLSLLI YAKRYLKERP FLSEHFRLPN LKILSLSNTL
ILFSLGFAFM SLFYTKANQV ESNQRKESVD ILFLVDVSLS MEALDVPPSR LSRAKDILLS
TAPDLVGNRL GIIAFAGSSF SFCPMTTDVS AFSDYVEALG VDLVAKKGTD MSQAFERASR
MLDSDKIWKN RLIVLISDGE EQESSKPIPW QADLIVWGLG TEEGGLIRFG NPDLNTSGYV
TQSGKLSQNP SDPDLIISKA NFDYLNEIAA RSNGKVYDLS FDNLGIGHFL NHIDSMKKNK
SQLISQIQKE EGAGPFLAIS AILFLLGLFF RMYHFTYLKH SLGAILILYA MSLSPVHAWE
LDPGGNRIKE GKEFFGEKKF KESKEAYQNA ETYFKEDHRL KFNKADVEHE LGQYDESIKL
NQEVIEDQHS SPDTKAKALY NQGNSYFKKN DLKNAFKSYE QALRINPNHE PSKRNLEFLK
QKSKAKQNSQ RQDESSKQEE QKQSPKERNQ QEQKPKNQER SDEQNTADKM MEQFDPNSIL
KKKPNYGGSS DNEKFW
//
