ID A0A2P2E753_9PROT Unreviewed; 206 AA.
AC A0A2P2E753;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=precorrin-2 dehydrogenase {ECO:0000256|ARBA:ARBA00012400};
DE EC=1.3.1.76 {ECO:0000256|ARBA:ARBA00012400};
GN Name=cysG_1 {ECO:0000313|EMBL:GBF56884.1};
GN ORFNames=PbB2_00541 {ECO:0000313|EMBL:GBF56884.1};
OS Candidatus Phycosocius bacilliformis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacterales incertae sedis; Phycosocius.
OX NCBI_TaxID=1445552 {ECO:0000313|EMBL:GBF56884.1, ECO:0000313|Proteomes:UP000245086};
RN [1] {ECO:0000313|EMBL:GBF56884.1, ECO:0000313|Proteomes:UP000245086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BOTRYCO-2 {ECO:0000313|EMBL:GBF56884.1,
RC ECO:0000313|Proteomes:UP000245086};
RA Tanabe Y., Yamaguchi H., Watanabe M.M.;
RT "Draft Genome Sequence of "Candidatus Phycosocius bacilliformis," an
RT Alphaproteobacterial Ectosymbiont of the Hydrocarbon-Producing Green Alga
RT Botryococcus braunii.";
RL Genome Announc. 6:e00396-18(2018).
CC -!- PATHWAY: Porphyrin-containing compound metabolism; siroheme
CC biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBF56884.1}.
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DR EMBL; BFBR01000001; GBF56884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P2E753; -.
DR OrthoDB; 9815856at2; -.
DR UniPathway; UPA00262; UER00222.
DR Proteomes; UP000245086; Unassembled WGS sequence.
DR GO; GO:0004325; F:ferrochelatase activity; IEA:InterPro.
DR GO; GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 1.10.8.610; SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like; 1.
DR InterPro; IPR028161; Met8-like.
DR InterPro; IPR042518; SirC_C.
DR PANTHER; PTHR35330; SIROHEME BIOSYNTHESIS PROTEIN MET8; 1.
DR PANTHER; PTHR35330:SF1; SIROHEME BIOSYNTHESIS PROTEIN MET8; 1.
DR Pfam; PF13241; NAD_binding_7; 1.
DR SUPFAM; SSF75615; Siroheme synthase middle domains-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:GBF56884.1}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000245086}.
FT REGION 185..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 206 AA; 21858 MW; DA6C58941BB11AEC CRC64;
MIPIHLDPAQ TRIGLVGRAE LTVRRLAWLR ALGGNPLVYS DQPDAILREA AGTALIARLP
TTSDLSEMQV IWVADLTPEE SEALGAQARA AKVLLNTEDV LPLCDFHTPS ILRRGRLVLS
AGTGGASPAA ASFVRERLAA SFPKEWAEML ESLAAERQAL KSAGATMAEM KQAALARLEA
TFGPATPYRG ETGNTSNAST IPPFGD
//
