ID   A0A2P2GQG5_9ACTN        Unreviewed;       394 AA.
AC   A0A2P2GQG5;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Methyltransferase {ECO:0000313|EMBL:KKZ73099.1};
GN   ORFNames=VO63_15080 {ECO:0000313|EMBL:KKZ73099.1};
OS   Streptomyces showdoensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68268 {ECO:0000313|EMBL:KKZ73099.1, ECO:0000313|Proteomes:UP000265325};
RN   [1] {ECO:0000313|EMBL:KKZ73099.1, ECO:0000313|Proteomes:UP000265325}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15227 {ECO:0000313|EMBL:KKZ73099.1,
RC   ECO:0000313|Proteomes:UP000265325};
RA   Thapa K.K., Metsa-Ketela M.;
RT   "Draft Genome assembly of Streptomyces showdoensis.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKZ73099.1}.
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DR   EMBL; LAQS01000020; KKZ73099.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P2GQG5; -.
DR   OrthoDB; 9810570at2; -.
DR   Proteomes; UP000265325; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR041497; Thump-like.
DR   PANTHER; PTHR14741; S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED; 1.
DR   PANTHER; PTHR14741:SF32; TRIMETHYLGUANOSINE SYNTHASE; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   Pfam; PF18096; Thump_like; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:KKZ73099.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265325};
KW   Transferase {ECO:0000313|EMBL:KKZ73099.1}.
FT   DOMAIN          105..172
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   DOMAIN          320..391
FT                   /note="THUMP-like"
FT                   /evidence="ECO:0000259|Pfam:PF18096"
SQ   SEQUENCE   394 AA;  41671 MW;  3655A5F8C9570DE4 CRC64;
     MGRVTDLAAF AALFSPEGQA LLAALRDYDP AQELAVASRL RREHPAELVS AALGQARLRQ
     RAVAKFGAED AYRMYFTPNG VEQSTRATVG AYRAARLKAL GVRSVADLCS GIGGDALALA
     RAGISVLAVD RDPLTAEAAR ANAAALGLDG LIEVRCADVT EIDTSPYDAV FVDPARRGGR
     GRIFDPEAYS PPLSWAVEAA RKAPHAALKI APGIPHEAVP EEAEAEWISD GGDVKEAVLW
     FGTEPGARRA TLLPGGATLT GGGLPDPEVR PVGRYLYEPD GAVIRAHLVA EVARELDGGL
     IDPTIAYVTA DALVPTPYAS AYEITDELPF NLKKLKALLR EREVGVLTVK KRGSAVEPEE
     IRRKVKPKGP NSATVLLTRV AGAPTMLIGR PAGR
//