ID A0A2P2GRA9_9ACTN Unreviewed; 1038 AA.
AC A0A2P2GRA9;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0000259|PROSITE:PS51755};
GN ORFNames=VO63_10360 {ECO:0000313|EMBL:KKZ74028.1};
OS Streptomyces showdoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68268 {ECO:0000313|EMBL:KKZ74028.1, ECO:0000313|Proteomes:UP000265325};
RN [1] {ECO:0000313|EMBL:KKZ74028.1, ECO:0000313|Proteomes:UP000265325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15227 {ECO:0000313|EMBL:KKZ74028.1,
RC ECO:0000313|Proteomes:UP000265325};
RA Thapa K.K., Metsa-Ketela M.;
RT "Draft Genome assembly of Streptomyces showdoensis.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ74028.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LAQS01000012; KKZ74028.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P2GRA9; -.
DR Proteomes; UP000265325; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000265325};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..94
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..94
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1038 AA; 107592 MW; B63944FB32833D11 CRC64;
MKFALLGPLR AWYRDQELDL GRPQQRALLA VLLDASGRAV AHDVLAEGVW GGGAGPADPR
KALQLLVYRL RSAFRPHLDE SPIVRVGDGY ALRAPGAWVD RGEWRRLLGE AERAGAAAGS
VERVAGAAAG SVERVAGAAA GSVERVAGAA DGSVERVAGA PAGPCEPVGS ALMGSVEPVG
SSLAGSARVR ELLRAALGLW VGEPLAGVGG PHAEAVRARL GEERLGVLER RLELDVELAD
RAELTAEAAA LCLEHPGRPR LVAVLMRALH RAGRTAEALA VFEDARGDLP PGDRGPDSPA
GLQLRILRDD PALLPAPAAQ PGPAWQAPRQ LPADLPDFTG RGGAVDELAE RLAGAGGRAV
VVSALDGMGG VGKTSLAVHA ARRAAGRFPD GQLFADLRGA DRAPREPAAV LAEFLRALGV
AAEEVPPGTA ERSACYRSAL TGRRVLVVLD NAAGPEQVEP LLPGSADCAV LVTSRTRLPG
LAGAHHLRID PLPAAEAAEL FTRIAGAERT AAEPGRVEEI VGACGRLPLA VRIAASRLAA
DPGLSLAALA EGLRDERRLA ALDDGERAVE ATFALSYHRL VPEAARAFRL LSLPDAPEIA
LPCAAALLDR TEAEADELLE GLVDLNLLQS PGFGRYGFHD LVRAYARDRA AEEETGAGRT
AAAGRLLDFC LATARNADTA ARSVDPAEQS LLGTPVTRPG RALATGPDAV RWMREQAAVH
AAAVALACAD EALPLAQAAE LVDKMGSVLF ERTQTSVIAA LADQVAEAAE ARDAHGPQAL
ARYVRGNMLW HVNRYEESRA EIARAVTLCG DGDGDGDTGT GAAARVRAKA LLTLAGNARI
HGRHAEAAEH AGRAAAAFRE LGAERAEGSA LGEFAFNAAH TGRLDEARRA AERGARLMSG
TGPVSAATGR YYLARVLRLC GDPEGALGHA LGAREEFARL QVAVFEAAAG DLAARLHAES
GRAALAAEAA EAVLPLARKT SAALEAALLH TLGSSLAVLG RPSQARACLQ DAAEVYGRLG
ITEEEAAVRA LLGGLPER
//
