ID A0A2P2GRH8_9ACTN Unreviewed; 453 AA.
AC A0A2P2GRH8;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=VO63_09620 {ECO:0000313|EMBL:KKZ74117.1};
OS Streptomyces showdoensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68268 {ECO:0000313|EMBL:KKZ74117.1, ECO:0000313|Proteomes:UP000265325};
RN [1] {ECO:0000313|EMBL:KKZ74117.1, ECO:0000313|Proteomes:UP000265325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15227 {ECO:0000313|EMBL:KKZ74117.1,
RC ECO:0000313|Proteomes:UP000265325};
RA Thapa K.K., Metsa-Ketela M.;
RT "Draft Genome assembly of Streptomyces showdoensis.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ74117.1}.
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DR EMBL; LAQS01000011; KKZ74117.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P2GRH8; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000265325; Unassembled WGS sequence.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265325}.
FT DOMAIN 190..443
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 32..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..66
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 46359 MW; B9798E77EEBD82DA CRC64;
MSLKPKPPHP LGTCPECAEP LESGDRFCGA CGYDLSAVPE PEPGTDRPTV PISLPVDWPE
PPPRDPQSLT TATQHPGDLP GTDSGGRDLP TVPVRTDGLP EPTAAATAAT AATAEPGGTG
GTGGTGSTGG SDGDFTLAAP DPRTALQGEG DDRKLCVACR TGRVDRDGYC EHCGHAQPRE
RDHMEEELAS VAAVSDRGLR HHRNEDAFAV SSTALPDGSP ATLAIVCDGV SSATRPDEAS
SAAASAAGAS LLAALPRGTH PQQAMHEAIV AAAEAVNSLA EETVKEREHQ NAPACTIVGS
IVAGGLLVVG WVGDSRAYWV PDDRTAPAAR LTEDDSWAAQ MVAAGLMNEA EAYADERAHA
ITGWLGADAY ELEPHTASFK PDRPGVVVVC TDGLWNYAEG AEDMARVVPP DAAGRPLHGA
QVLVGHALDG GGHDNVTVAL LPFALPSAGA GSA
//
