ID A0A2P2SXF2_9PEZI Unreviewed; 520 AA.
AC A0A2P2SXF2;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=VE01_00151 {ECO:0000313|EMBL:OBU01511.1};
OS Pseudogymnoascus verrucosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=342668 {ECO:0000313|EMBL:OBU01511.1, ECO:0000313|Proteomes:UP000091956};
RN [1] {ECO:0000313|EMBL:OBU01511.1, ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|EMBL:OBU01511.1,
RC ECO:0000313|Proteomes:UP000091956};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|Proteomes:UP000091956};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; KV460206; OBU01511.1; -; Genomic_DNA.
DR RefSeq; XP_018135243.1; XM_018269684.1.
DR AlphaFoldDB; A0A2P2SXF2; -.
DR STRING; 342668.A0A2P2SXF2; -.
DR GeneID; 28833537; -.
DR OrthoDB; 1743223at2759; -.
DR Proteomes; UP000091956; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF423; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000091956};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 21..520
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5015021928"
FT DOMAIN 28..370
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 393..504
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 520 AA; 56209 MW; D7C4E998675F0BCD CRC64;
MKLSDVLFGA ILCISAPVRG EWTVGQGVYT PSGLVLGSAA SKLPSVSVYR GIPYAQPPIG
ELRFAAPLPF SGNTHLPFSD SPSIDGTKFG ASCPVSSYFA GKPVTKGKGL SAAGLATLAQ
LTKGNNDTSE DCLTLNVWTK PQTGEEKKAV VIWVHGKGYT TGSSSDPVYD GQFIVNEQDI
ILVTFNYRMN IFGFPGSYLN TRNIGLLDQR LAVEWVRDNI AGFGGDPARI TLIGDSAGAG
LVDLYSFAYV DDPIISSMGL LSGTTSLSGW DPDSLPKAER DWNSVTCDIC RMGTETDFAK
VIACMRNKTT AEITAAIPIT TNPYGSKSFF PNNDGKTVFS DYYELARTGK FIKVPLLIGN
TDDETAYHRI MADVFAPSYG YGQTNYDNER RNYYTCPASE RARHTADLGV PTWRYGYFGD
FKDARLTTAA HGRAYHGSDV LLIFGTELVP GVKQDADELK LAKYARGAVA AFARNPKTGL
KTYGWPQYNP KAKSLVQLGK DNKVGTFAVT PAAFDTGCLY
//
