ID   A0A2P2SYD6_9PEZI        Unreviewed;       997 AA.
AC   A0A2P2SYD6;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Hydantoinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VE01_00379 {ECO:0000313|EMBL:OBU01837.1};
OS   Pseudogymnoascus verrucosus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=342668 {ECO:0000313|EMBL:OBU01837.1, ECO:0000313|Proteomes:UP000091956};
RN   [1] {ECO:0000313|EMBL:OBU01837.1, ECO:0000313|Proteomes:UP000091956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 10579 {ECO:0000313|EMBL:OBU01837.1,
RC   ECO:0000313|Proteomes:UP000091956};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000091956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 10579 {ECO:0000313|Proteomes:UP000091956};
RX   PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT   white-nose syndrome of bats.";
RL   Nat. Commun. 9:35-35(2018).
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DR   EMBL; KV460206; OBU01837.1; -; Genomic_DNA.
DR   RefSeq; XP_018135569.1; XM_018269911.1.
DR   AlphaFoldDB; A0A2P2SYD6; -.
DR   STRING; 342668.A0A2P2SYD6; -.
DR   GeneID; 28833765; -.
DR   OrthoDB; 307246at2759; -.
DR   Proteomes; UP000091956; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 2.40.390.10; CV3147-like; 1.
DR   Gene3D; 3.40.1610.10; CV3147-like domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR048350; DUF917_C.
DR   InterPro; IPR024071; DUF917_C_sf.
DR   InterPro; IPR010318; DUF917_N.
DR   InterPro; IPR027479; DUF917_N_sf.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF10; HYDANTOINASE; 1.
DR   Pfam; PF06032; DUF917; 1.
DR   Pfam; PF20906; DUF917_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF160991; CV3147-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000091956}.
FT   DOMAIN          9..189
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          210..385
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          607..766
FT                   /note="DUF917"
FT                   /evidence="ECO:0000259|Pfam:PF06032"
FT   DOMAIN          771..983
FT                   /note="DUF917"
FT                   /evidence="ECO:0000259|Pfam:PF20906"
SQ   SEQUENCE   997 AA;  106812 MW;  7C093B060478E62F CRC64;
     MGSILPLYRI GVDVGGTNTD AVILDPNGAL WENRGVVAFH KTSTTSPNVT NGIESAVRAV
     IEQSGISLGQ ISSICIGTTH FINAVVEHDA KQLSKVAVIR LSKSYTRDIP PFSDFPPALA
     KLMNGYYGYV NGGLHIDGSQ ESPVLKDQVI QQCNIIKEKG LNTIVICGVF SPIDTHFRQE
     HQVRNIVLEQ LPGADVVCSS EVANMGFLER ENASILNASI LKFARRTIAS FKAAMRRLQL
     DCPLYLTQND GTLIDAAAAA RLPIRTFSSG ATNSMRGAAY LGLSSSQGTK NTSAIVIDIG
     GTTSDVGVLL PSGYPRQASA FVTVAGIRIN YNMPHVESIG LGGGSIIKVN VHGDVTVGPT
     SVGYQLTTKA KIFHGDVLTA TDIAVAHDPS IKIGNPALVK DVSTENITQA RRKMKVMLER
     VIDIMKTSPD PLPVLLVGGG SAIAPNELDG VSTIIRPPFH QVANAVGAAI SKAGSTVDII
     QSTANQTVAD ALEHAKLAAI EAAVAIGAIR GTISITEMGS IPLQYVEHQI RTLVRVAGDL
     STDFAAVDDI TSDHLHDEEH EDEAISVESK HKRCIEDAPK PLDIETYRPK IITNSETGIS
     EWIISETDLI WLADGCYVLG CAGGGTPLPE FLKLRDQVRA GHIIRVVDAS SLAKDARIYW
     GGNMGSPAVS AERLSAGELL ECIDEMMYYL RHDSFDAVMS VEIGGANGLQ PLLWGSSKNY
     NRVCVDADLM GRAYPNYWQN TLTAHESGQL VPCAIASGNG KAMIMTRTDE DLDVDRVLRA
     PAIEMGSYVG MIGKPTTADH VERYGVLNTM SSAWRIGRCI NRAKLSNTIG TVTDQIIDEL
     GGSSAAKLLF TGKIIGVERK LLKGHSYGEV IVEEMPASEE DKRKLAYAPT AQGGQLRVPF
     KNENIYAKHI AEDGTETFVA MVPDLIAILD AQTGKALGVP EFRYGVIVHV LGIAASPRWT
     DSPRGLEIGG LGAFGYDIPY KPLGTYVKPK SVVLEFA
//