ID A0A2P4THB3_BAMTH Unreviewed; 535 AA.
AC A0A2P4THB3;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};
GN ORFNames=CIB84_000511 {ECO:0000313|EMBL:POI35747.1};
OS Bambusicola thoracicus (Chinese bamboo-partridge) (Perdix thoracica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Perdicinae; Bambusicola.
OX NCBI_TaxID=9083 {ECO:0000313|EMBL:POI35747.1, ECO:0000313|Proteomes:UP000237246};
RN [1] {ECO:0000313|EMBL:POI35747.1, ECO:0000313|Proteomes:UP000237246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RTK389 {ECO:0000313|EMBL:POI35747.1};
RC TISSUE=Blood {ECO:0000313|EMBL:POI35747.1};
RA Tiley G.P., Kimball R.T., Braun E.L., Burleigh J.G.;
RT "Comparison of the Chinese Bamboo Partridge and Red Junglefowl genome
RT sequences highlights the importance of demography in genome evolution.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Directly regulates filament dynamics and has been implicated
CC in a number of complex developmental and morphological processes,
CC including mRNA localization and the establishment of cell polarity.
CC {ECO:0000256|ARBA:ARBA00003250}.
CC -!- SUBUNIT: Homodimer. Binds actin monomers.
CC {ECO:0000256|ARBA:ARBA00026058}.
CC -!- SIMILARITY: Belongs to the CAP family. {ECO:0000256|RuleBase:RU000647}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POI35747.1}.
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DR EMBL; PPHD01000239; POI35747.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P4THB3; -.
DR Proteomes; UP000237246; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.25.40.330; Adenylate cyclase-associated CAP, N-terminal domain; 1.
DR InterPro; IPR001837; Adenylate_cyclase-assoc_CAP.
DR InterPro; IPR013912; Adenylate_cyclase-assoc_CAP_C.
DR InterPro; IPR013992; Adenylate_cyclase-assoc_CAP_N.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR028417; CAP_CS_C.
DR InterPro; IPR018106; CAP_CS_N.
DR InterPro; IPR036222; CAP_N_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10652; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR10652:SF1; ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF08603; CAP_C; 1.
DR Pfam; PF01213; CAP_N; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SMART; SM00673; CARP; 2.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF101278; N-terminal domain of adenylylcyclase associated protein, CAP; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
DR PROSITE; PS01088; CAP_1; 1.
DR PROSITE; PS01089; CAP_2; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000237246};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 375..513
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
FT COILED 179..206
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 535 AA; 59035 MW; 4D9CE0062B78E612 CRC64;
MDGLRAAAVG LRETNPASVP PQSAVPFLIV VVVLDSNLVV TYIVAVAAGI SVAAAFLLPW
SMLPDVIDDF KLQHPESRGH EAIFFSFYVF FTKFTSGVSL GISTLSLDFA GYQTRGCSQP
SEVNITLKLL VSAVPVGLIL LGLLLFKLYP IDEEKRRENK KALQDLSFVP SEDVSNRSLS
VQAEDIAAME RLVERLERAV ERLETVCQGP GMCGDGSSPG VAQYVQAFDA ILSGPVAEYI
NISKEVGGDV QKHAEMVHAG FMTERSLLVT ASQHQQPSEN VFSTLLKPIS EQIQMVQNLR
EKNRGSKQFN HLSAVSESIP ALGWVAMSPK PGPYVKEMTD AAMFYTNRIL KEYKDVDKKQ
VDWVKAYLRI WTELQAYIKE YHTTGLTWSK TEHQENATNL VINDTELKQV AYVFKCTNST
LQIKGKINSI TLDNCKKLGL VFDDVVGIVE IINSRDIKVQ VMGKVPTISI NKTDGCHVYL
SKNSLDCEIV SAKSSEMNVL IPTEGGDFTE FPVPEQFKTV WNGQKLVTTV TEIAG
//
