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Database: UniProt
Entry: A0A2P4UE28_9ACTN
LinkDB: A0A2P4UE28_9ACTN
Original site: A0A2P4UE28_9ACTN 
ID   A0A2P4UE28_9ACTN        Unreviewed;       125 AA.
AC   A0A2P4UE28;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Penicillinase repressor {ECO:0000313|EMBL:POM23305.1};
GN   ORFNames=BTM25_44580 {ECO:0000313|EMBL:POM23305.1};
OS   Actinomadura rubteroloni.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=1926885 {ECO:0000313|EMBL:POM23305.1, ECO:0000313|Proteomes:UP000242367};
RN   [1] {ECO:0000313|EMBL:POM23305.1, ECO:0000313|Proteomes:UP000242367}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-2 {ECO:0000313|EMBL:POM23305.1,
RC   ECO:0000313|Proteomes:UP000242367};
RX   PubMed=28463423; DOI=10.1002/chem.201701005;
RA   Guo H., Benndorf R., Leichnitz D., Klassen J.L., Vollmers J., Gorls H.,
RA   Steinacker M., Weigel C., Dahse H.M., Kaster A.K., de Beer Z.W.,
RA   Poulsen M., Beemelmanns C.;
RT   "Isolation, Biosynthesis and Chemical Modifications of Rubterolones A-F:
RT   Rare Tropolone Alkaloids from Actinomadura sp. 5-2.";
RL   Chemistry 23:9338-9345(2017).
CC   -!- SIMILARITY: Belongs to the BlaI transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00011046}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POM23305.1}.
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DR   EMBL; MTBP01000003; POM23305.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P4UE28; -.
DR   Proteomes; UP000242367; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005650; BlaI_family.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF03965; Penicillinase_R; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242367}.
SQ   SEQUENCE   125 AA;  13509 MW;  3F4D9A595643492D CRC64;
     MDEGTGARRP AGALEAELLA VLQSAEAALT PGDVAGRMGG ELSYSTVVTV LSRMHAKGTL
     NRERSGRAYA YSPVLDAAGM AARRMREVLE NERDRDAVLT RFVGELSPRD EALFRRLLSS
     DDGQE
//
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