ID A0A2P4UL79_9ACTN Unreviewed; 424 AA.
AC A0A2P4UL79;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nitrilotriacetate monooxygenase component A {ECO:0000313|EMBL:POM25802.1};
DE EC=1.14.14.10 {ECO:0000313|EMBL:POM25802.1};
GN Name=ntaA_1 {ECO:0000313|EMBL:POM25802.1};
GN ORFNames=BTM25_01850 {ECO:0000313|EMBL:POM25802.1};
OS Actinomadura rubteroloni.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1926885 {ECO:0000313|EMBL:POM25802.1, ECO:0000313|Proteomes:UP000242367};
RN [1] {ECO:0000313|EMBL:POM25802.1, ECO:0000313|Proteomes:UP000242367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-2 {ECO:0000313|EMBL:POM25802.1,
RC ECO:0000313|Proteomes:UP000242367};
RX PubMed=28463423; DOI=10.1002/chem.201701005;
RA Guo H., Benndorf R., Leichnitz D., Klassen J.L., Vollmers J., Gorls H.,
RA Steinacker M., Weigel C., Dahse H.M., Kaster A.K., de Beer Z.W.,
RA Poulsen M., Beemelmanns C.;
RT "Isolation, Biosynthesis and Chemical Modifications of Rubterolones A-F:
RT Rare Tropolone Alkaloids from Actinomadura sp. 5-2.";
RL Chemistry 23:9338-9345(2017).
CC -!- SIMILARITY: Belongs to the NtaA/SnaA/DszA monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00033748}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POM25802.1}.
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DR EMBL; MTBP01000001; POM25802.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P4UL79; -.
DR Proteomes; UP000242367; Unassembled WGS sequence.
DR GO; GO:0018529; F:nitrilotriacetate monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0102977; F:nitrilotriacetate monooxygenase activity (FMN-dependent); IEA:UniProtKB-EC.
DR CDD; cd01095; Nitrilotriacetate_monoxgenase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR016215; NTA_MOA.
DR NCBIfam; TIGR03860; FMN_nitrolo; 1.
DR PANTHER; PTHR30011; ALKANESULFONATE MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR30011:SF16; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR PIRSF; PIRSF000337; NTA_MOA; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000337-1};
KW FMN {ECO:0000256|PIRSR:PIRSR000337-1};
KW Monooxygenase {ECO:0000313|EMBL:POM25802.1};
KW Oxidoreductase {ECO:0000313|EMBL:POM25802.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242367}.
FT DOMAIN 18..376
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT BINDING 52
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 89
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 139
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 143
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 213
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 214
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
SQ SEQUENCE 424 AA; 46363 MW; 305C28DD05EB04FB CRC64;
MHLNAFLMPA GHHDAAWRHP SSGADRATDV AYYQDLARTA ERGRLDSVFF ADGVAIRPAP
AANVAGGLEP LTLLAALAVV TSRVGLIATA STTFYEPYTL ARAFASLDHI SGGRAGWNIV
TSGTEAEARN FNRDTHLDHA VRYQRAAEFV DVANALWESW EPDAIVFDRD AGVYADPSKI
HDVGHTGEHF RVRGPLNVPR SPQGRPLLVQ AGSSEDGRAF AARHAEAIFT AQQTLADGQA
FYRDVKARAA RHGRDPRILP GICPVLGSTE EEAHRLSESL TELQVLDYGL EQLSGMLNVD
LSGYPLDGPL PDVLPSEDEI NGNKSRFTLV ARLARREKLT IRQIIARLGG GRGHRVFAGT
PEQVADELEE WHRLGAADGF NIMPPVLPTG LEDFVDHVVP LLQKRGLFRH EYESTTLRGH
YGLD
//
