ID   A0A2P4XKR2_9STRA        Unreviewed;       929 AA.
AC   A0A2P4XKR2;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:POM66127.1};
GN   ORFNames=PHPALM_18060 {ECO:0000313|EMBL:POM66127.1};
OS   Phytophthora palmivora var. palmivora.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=611791 {ECO:0000313|EMBL:POM66127.1, ECO:0000313|Proteomes:UP000237271};
RN   [1] {ECO:0000313|EMBL:POM66127.1, ECO:0000313|Proteomes:UP000237271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=sbr112.9 {ECO:0000313|Proteomes:UP000237271};
RC   TISSUE=Mycelia {ECO:0000313|EMBL:POM66127.1};
RX   PubMed=28186564;
RA   Ali S.S., Shao J., Lary D.J., Kronmiller B., Shen D., Strem M.D.,
RA   Amoako-Attah I., Akrofi A.Y., Begoude B.A., Ten Hoopen G.M., Coulibaly K.,
RA   Kebe B.I., Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W.,
RA   Bailey B.A.;
RT   "Phytophthora megakarya and P. palmivora, closely related causal agents of
RT   cacao black pod rot, underwent increases in genome sizes and gene numbers
RT   by different mechanisms.";
RL   Genome Biol. Evol. 9:536-557(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POM66127.1}.
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DR   EMBL; NCKW01009733; POM66127.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P4XKR2; -.
DR   OrthoDB; 49911at2759; -.
DR   Proteomes; UP000237271; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase {ECO:0000313|EMBL:POM66127.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237271};
KW   RNA-directed DNA polymerase {ECO:0000313|EMBL:POM66127.1};
KW   Transferase {ECO:0000313|EMBL:POM66127.1}.
FT   DOMAIN          537..640
FT                   /note="Reverse transcriptase RNase H-like"
FT                   /evidence="ECO:0000259|Pfam:PF17917"
FT   DOMAIN          704..824
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|Pfam:PF13456"
FT   REGION          128..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          906..929
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  105141 MW;  D69587BA0616CB73 CRC64;
     MKVYELKTKM SPAVRNWYGQ LSKHVRTEWS RLSKEFKREY CKSRVSESEK YYTMKQFKDE
     TALAFLYRLN LAAERADVCF RKSERRREQH IKRFINNLTD VTLKTTLQSQ RLRKVSDLEY
     VLKQQEEVNP SGVHSGRGTQ PRDFRADNVA RNGPRMNRPN RAYVAQDDEA QGSDTQVTFE
     DDERADLAAL STCVQDVLRD GNPDTRLFTR EDLIHEVYRV MNSVGLKLKL NSQKRIKVSG
     LGGVPTYITA STQIKVTLGR RVVYILDVWV TNIGEGVDVL LRMDIMYSAG VRLCIREGTM
     ALPDEESVLM YGYMVRKHRD RNVPITPLQD VHLRPGEHVN VKIRSGMPLK EILKRHRSIF
     LGDGNAAPAP ARGMVCDLDV GDAKPVAQRP RPVVPQVAIK VYELLKKLLE TKLIEHSESP
     WASPIVIVLK KNGVDIRMCI DYRVVNSFIR LSNYPLPLID DLLTGLESAM WFMSLDMASG
     SLNYYHKFIE DFPVVAAVLY ELSDEQVRAG RDLSRAKEEF DILKQKIVST PLLRHPDRTK
     PFVIIPHANQ WAACAVLGQE HDGVIQPVRF TGRVLNDAEL RYHIAEKEVL AVIRILHVFK
     TLIEGCPLVI YTRHLVLKWV IKSKTADGHL VPWGVALSQY DLEIRKIQRD EDGLAAILGA
     GITPREHLDK IAEALIPAKG RVKAPPVISI EKLEADYSGM VLSFDGAAKT STRIGSCGCV
     LWQLPEWKVL DARGYILDGV TVNDAEYFGL IRGLAMARDR GIQDLVVVGD SRIVIQQVQG
     LINCNQPNLQ SRLAECEVLK KRFNSVRLVH VKREFNQAAD YLTSKTLTLG NSWVVEEDAE
     REHLEVVSRI QEQLMKASDE ETKSNSEMPR NSPNVLTMRV SGDGALHGPE YEPLPPAARV
     LAAFTRSRAR TREGESASPM GPLEYQAER
//