ID A0A2P4ZQV8_9HYPO Unreviewed; 1116 AA.
AC A0A2P4ZQV8;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Nitrite reductase {ECO:0000313|EMBL:PON26653.1};
GN ORFNames=TGAM01_v204663 {ECO:0000313|EMBL:PON26653.1};
OS Trichoderma gamsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=398673 {ECO:0000313|EMBL:PON26653.1, ECO:0000313|Proteomes:UP000054821};
RN [1] {ECO:0000313|EMBL:PON26653.1, ECO:0000313|Proteomes:UP000054821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6085 {ECO:0000313|EMBL:PON26653.1,
RC ECO:0000313|Proteomes:UP000054821};
RX PubMed=26893428;
RA Baroncelli R., Zapparata A., Piaggeschi G., Sarrocco S., Vannacci G.;
RT "Draft Whole-Genome Sequence of Trichoderma gamsii T6085, a Promising
RT Biocontrol Agent of Fusarium Head Blight on Wheat.";
RL Genome Announc. 4:e01747-15(2016).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
CC -!- PATHWAY: Nitrogen metabolism; nitrate reduction (assimilation).
CC {ECO:0000256|ARBA:ARBA00005096}.
CC -!- SIMILARITY: Belongs to the nitrite and sulfite reductase 4Fe-4S domain
CC family. {ECO:0000256|ARBA:ARBA00010429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON26653.1}.
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DR EMBL; JPDN02000013; PON26653.1; -; Genomic_DNA.
DR RefSeq; XP_018662253.1; XM_018804440.1.
DR AlphaFoldDB; A0A2P4ZQV8; -.
DR STRING; 398673.A0A2P4ZQV8; -.
DR GeneID; 29984523; -.
DR OrthoDB; 275583at2759; -.
DR UniPathway; UPA00653; -.
DR Proteomes; UP000054821; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-UniPathway.
DR CDD; cd19944; NirB_Fer2_BFD-like_2; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR InterPro; IPR012748; Rieske-like_NirD.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR NCBIfam; TIGR02378; nirD_assim_sml; 1.
DR PANTHER; PTHR43809; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR PANTHER; PTHR43809:SF1; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF01077; NIR_SIR; 1.
DR Pfam; PF03460; NIR_SIR_ferr; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF13806; Rieske_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00397; SIROHAEM.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 1.
DR PROSITE; PS00365; NIR_SIR; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054821}.
FT DOMAIN 935..1047
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
FT REGION 1090..1116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 122836 MW; BD3816CB4D489A27 CRC64;
MNTAAADMRP ESAAIQPRHK KRAAVIGLGM VGISFIEKLL KYDLDSGRDE WEVTVFGEEP
YVAYNRVGLT QYFTNRSTES LYLNPLEWYS SHSKGKLTYH TSDLVITIDS HAKCLKTASG
QQFHYDECIL ATGSDAALPP YISPQQFKNA RGCFVYRTIK DLDNIIDYAV SAPAVIGRRI
RKAAVIGGGL LGLEAAKALL DLEEVDQVVL VERNRWVLSR QLDQEGGSLV LEKIKSLGVE
VLIQARVQNL LWDSEKRLSG LLLQGQDGSP DQQYDVDMVV FAVGIKPRDD LAKGTSIDTA
NHNGGFIVDN QLRTNLPHIY AIGECANFLG ETFGLIAPGI EMADILAFNL TEGPYHSKRE
MKSPNISTKL KLMGVDVASF GDFFADQGKI SKPLPGATGA HAARKAQTTP PTPEDIKKKV
KALIYRDPFS DVYKKYIFTA DGKYILGGMM VGEVKDYVKL VALCNASKPI EKPPAEFIIG
AAKEGEEEGD DLPHDTQVCS CHNVSKGDIV ECVKSGGIRS FGEMKSSTKC GMGCGGCVPL
ATSIFNRALK DAGVEISNHI CKDFAYSRQE LYQIAKFRKL KDFVAVMRAA GKKSDSLGCE
VCRPAIGSIL SSLYNENIMK PSLRQTQDTN DRYLANVQRD GSYSVVPRLP AGEITPMGLK
VIGEVADKYG LYTKITGGQR IDMFGAKKQD LPQIWELLIN AGFESGHAYG KALRTVKSCV
GNTWCRFGVG DSVGLAVEIE NRYKGLRAPH KFKGGVSGCV RECAEAQGKD FGLIATPKGW
NVFVGGNGGA KPRHAELLAE DVTRRQAIKI LDRFLMFYIQ SADKLERTAR WIERYPGGLK
GIKEVIVDDR LGICADLEKE MEVLVGLYHC EWTNVVNNPD RRKDFKQFAN TDETQTSSEH
IMERAQKRPA DWPEDSSPLH FSLLDIAKDA KWAWRSVCKL SELNRQSDAP TSVAVKYGEV
QLAVWNIPGR GLRASQNMCP HKKAFVLADG LVGEDEKGRE YVSCPLHKRN FLLNPNAAEG
GGSCSDVDYS IMTFEVKADE TNNEILIYLP PTEALDAVLS TTKWMLRKAD EELKALAKDA
EPAIEIAEPL PPSKMRGQPP HLASRQTCGG SGALDW
//
