ID A0A2P5A2P1_9HYPO Unreviewed; 447 AA.
AC A0A2P5A2P1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:PON30784.1};
GN ORFNames=TGAM01_v200204 {ECO:0000313|EMBL:PON30784.1};
OS Trichoderma gamsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=398673 {ECO:0000313|EMBL:PON30784.1, ECO:0000313|Proteomes:UP000054821};
RN [1] {ECO:0000313|EMBL:PON30784.1, ECO:0000313|Proteomes:UP000054821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6085 {ECO:0000313|EMBL:PON30784.1,
RC ECO:0000313|Proteomes:UP000054821};
RX PubMed=26893428;
RA Baroncelli R., Zapparata A., Piaggeschi G., Sarrocco S., Vannacci G.;
RT "Draft Whole-Genome Sequence of Trichoderma gamsii T6085, a Promising
RT Biocontrol Agent of Fusarium Head Blight on Wheat.";
RL Genome Announc. 4:e01747-15(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON30784.1}.
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DR EMBL; JPDN02000001; PON30784.1; -; Genomic_DNA.
DR RefSeq; XP_018657633.1; XM_018809156.1.
DR AlphaFoldDB; A0A2P5A2P1; -.
DR STRING; 398673.A0A2P5A2P1; -.
DR GeneID; 29989239; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000054821; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054821}.
FT DOMAIN 6..120
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 124..439
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 447 AA; 48900 MW; CADCF394995A6F9F CRC64;
MAQQSVLMLG AGFVTRPTLD VLTDAGIPVT VACRTLQTAQ GLSAGVKLAT PISLDVTDAK
ALDAEVAKHD LVISLIPYTF HATVIESAIR QKKNVVTTSY VSPAMMELDQ KAKDAGITVM
NEIGLDPGID HLYAVKTIDE VHQAGGKILS FLSYCGGLPA PEASDNPLGY KFSWSSRGVL
LALRNAAKVY QNGKIVDIAS KDLMATAKPY FIMPGYAFVA YPNRDSTPYK ERYNIPEAET
IVRGTLRYQG FPQFIKVLVQ TGFLEETPIE ALKTPIAWKE ATKAVLGISS SEPKDLEAAI
VSRADFDSDE DRERILSGLR WIGIFSDEKI TPRGNSLDTL CATLEQKMQF EENERDMVML
QHKFEIEHKD GSRETRTSTL VEYGDPKGYS AMAKLVGVPA AVATKQVLDG TLSEKGVLAP
MTAKINNPIM KELKEKYGIT MIEKTVL
//
