ID   A0A2P5AE50_PARAD        Unreviewed;       636 AA.
AC   A0A2P5AE50;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cytochrome P450, E-class, group I {ECO:0000313|EMBL:PON34823.1};
GN   ORFNames=PanWU01x14_341220 {ECO:0000313|EMBL:PON34823.1};
OS   Parasponia andersonii (Sponia andersonii).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Cannabaceae; Parasponia.
OX   NCBI_TaxID=3476 {ECO:0000313|EMBL:PON34823.1, ECO:0000313|Proteomes:UP000237105};
RN   [1] {ECO:0000313|Proteomes:UP000237105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. WU1-14 {ECO:0000313|Proteomes:UP000237105};
RA   Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA   Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA   Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA   Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA   Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA   Smit S., Geurts R.;
RT   "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT   legume Parasponia.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PON34823.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JXTB01000641; PON34823.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P5AE50; -.
DR   STRING; 3476.A0A2P5AE50; -.
DR   OrthoDB; 3217781at2759; -.
DR   Proteomes; UP000237105; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11064; CYP86A; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24296; CYTOCHROME P450; 1.
DR   PANTHER; PTHR24296:SF111; CYTOCHROME P450 FAMILY PROTEIN-RELATED; 1.
DR   Pfam; PF00067; p450; 2.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 2.
DR   PROSITE; PS00086; CYTOCHROME_P450; 2.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   636 AA;  74116 MW;  F6C5744592E59E36 CRC64;
     MDFFSAVSFF FLFLLSLYVY LHFHTIPNKR SIRTGFKIYP IVGTLPGFLK NRHRLLEWFT
     ETLIKTPTNT AVLRRPGSVY AVTTANPLNV EHMLKTNFEN YPKGDGFIIV LRDFLGRGIF
     NSDGELWKVQ RKTASYEFNT KSLRNFAMEN VVVELETRLI PALEKASETD RVMDLQDVLE
     RFAFDNVCKL AFDVDPGCLG GDGTAGAEFM QAFEDAAMLS SGRFRYSFPY FWKVKRFLNV
     GTERRLRESI STVHEFADNI IRSRMESRLE QTEDLLSRFV GNEYDKSPEF LRDIVISFIL
     AGRDTTSSAL TWFFWLLSSR PEIQENILKE LETTRLQNRK NMGETFSFGE LRNLQYLHAA
     LSESMRLYPP VPVDTKVCQN DDVLPDGTFV GKDWLVTYHT FAMGRMEKIW GKDCWEFRPE
     RWLKDGVFHQ ESPFWYPIFH AGPRICLGKD MAYIQMKSIA ASLIERFEID VLNKDTFPGY
     IQSLTLRMKG GLPIRVRRRR IFVDTKVCQN DDVLPDGTFV GKDWLVTYHT FAMGRMEKIW
     GKDCWEFRPE RWLKDGVFHQ ESPFWYPIFH AGPRICLGKD MAYIQMKSIA ASLIERFEIN
     VLNKDTFPGY IQSLTLRMKG GLPIRVRRRR IFGTPN
//