ID A0A2P5AW94_PARAD Unreviewed; 1029 AA.
AC A0A2P5AW94;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Ubiquitin conjugation factor E4, core {ECO:0000313|EMBL:PON40797.1};
GN ORFNames=PanWU01x14_294880 {ECO:0000313|EMBL:PON40797.1};
OS Parasponia andersonii (Sponia andersonii).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Cannabaceae; Parasponia.
OX NCBI_TaxID=3476 {ECO:0000313|EMBL:PON40797.1, ECO:0000313|Proteomes:UP000237105};
RN [1] {ECO:0000313|Proteomes:UP000237105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. WU1-14 {ECO:0000313|Proteomes:UP000237105};
RA Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA Smit S., Geurts R.;
RT "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT legume Parasponia.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ubiquitin conjugation factor E4 family.
CC {ECO:0000256|ARBA:ARBA00007434}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON40797.1}.
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DR EMBL; JXTB01000432; PON40797.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5AW94; -.
DR STRING; 3476.A0A2P5AW94; -.
DR OrthoDB; 1554at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000237105; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IEA:InterPro.
DR CDD; cd16657; RING-Ubox_UBE4A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR019474; Ub_conjug_fac_E4_core.
DR InterPro; IPR045132; UBE4.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13931:SF2; UBIQUITIN CONJUGATION FACTOR E4 B; 1.
DR PANTHER; PTHR13931; UBIQUITINATION FACTOR E4; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF10408; Ufd2P_core; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000237105}.
FT DOMAIN 931..1005
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REGION 435..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 510..537
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1029 AA; 116376 MW; F959D422081DE3CD CRC64;
MATPKPQRSP EEVEDIILRK IFLVSLTETA AESDSRVVYL ELTAAEILSE GKELRLSRDL
MERVLIDRLS GNFASAEPPF QYLIGCYRRA CDEGKKIASI KDNNLRSEME SAARQAKKLS
VSYCRIHLAN PELFSAANSS PNRPNGSPLL PLIFSKVGSS LDGFGGVVGG SGGVESPPGF
LEEFFRDSDF DSLDPILRGL YEDLRLGVLK VSALGNFQQH LRALHFLVSL PVGAKSLVNH
PWWIPKGVYL TGRAIEVTSV LGPFFHVSAL PDHTIYKSQP DVGQQCFSDA STRRPADLLS
SFTTIKTVMN NLYDGLSEVL LLLLKNQDTR QGVLEFFAEV INKNSSRAHI QVDPMSCASS
GMFVNLSAVM LRLCEPFLDA NLTKRDKIDP KYVFYGDRLD LGGLTALHAS SEEVAEWTNK
RQSDGENRLL QSQEATSSGI NTFGPPITKS SSSGEKTKYT FICECFFMTA RVLNLGLLKA
FSDFKHLVQD ISRREDALTT LKDMQGQTPS PQLQLEITRL EKEIELFSQE KLCYEAQILR
DGTIIQCALS FYRLMVVWLV GMVGGFKMPL PSTCPTEFAC MPEHFVEDAM ELLIFASRIP
KALDGVLLDD FMNFIIMFMA SPNYIRNPYL RAKMVEVLNC WMPRRSGSSA TASLFEGHQL
SLEYLVRNLL KLYVDIEFTG SHTQFYDKFN IRHNIAELLE YLWQVPSHRN AWRRIAKEEE
KGVYLNFLNF LINDSIYLLD ESLNKILELK ELEAEMANTA EWERRPAQER QERTRLFHSQ
ENIIRIDMKL ANEDVSMLAF TSEQITAPFL LPEMVERVAS MLNYFLLQLV GPQSKSLSLK
DPEKYEFRPK QLLKQIVCIY VHLARGDSEN IFPSAISKDG RSYNEQLFTD AADVLRRIGE
NGKVIQEFDE LSAKAKVAAS EARDAEATLG EIPDEFLDPI QYTLMRDPVI LPSSRITIDR
AVIQRHLLSD STDPFNRSHL TADMLIPDTE LKERIEEFIR SQEMKRREGL STQSIKATIQ
TTDGQMLID
//
