ID   A0A2P5C7H9_PARAD        Unreviewed;       543 AA.
AC   A0A2P5C7H9;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Isopenicillin N synthase {ECO:0000313|EMBL:PON56999.1};
GN   ORFNames=PanWU01x14_177290 {ECO:0000313|EMBL:PON56999.1};
OS   Parasponia andersonii (Sponia andersonii).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Cannabaceae; Parasponia.
OX   NCBI_TaxID=3476 {ECO:0000313|EMBL:PON56999.1, ECO:0000313|Proteomes:UP000237105};
RN   [1] {ECO:0000313|Proteomes:UP000237105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. WU1-14 {ECO:0000313|Proteomes:UP000237105};
RA   Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA   Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA   Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA   Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA   Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA   Smit S., Geurts R.;
RT   "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT   legume Parasponia.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PON56999.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JXTB01000164; PON56999.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P5C7H9; -.
DR   STRING; 3476.A0A2P5C7H9; -.
DR   OrthoDB; 1057251at2759; -.
DR   Proteomes; UP000237105; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR026992; DIOX_N.
DR   InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR   InterPro; IPR027443; IPNS-like_sf.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   PANTHER; PTHR10209:SF847; FI07970P-RELATED; 1.
DR   PANTHER; PTHR10209; OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF03171; 2OG-FeII_Oxy; 2.
DR   Pfam; PF14226; DIOX_N; 2.
DR   PRINTS; PR00682; IPNSYNTHASE.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 3.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237105}.
FT   DOMAIN          270..380
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
SQ   SEQUENCE   543 AA;  61717 MW;  2E40135CE1990B91 CRC64;
     MYRAEEPHTI NRGVGRHKDG GAVTVLAQDD VGGLEVRRKS DGEWILVIPT PDAFIINVGD
     IIQDRIGVSY SKIKNQEIIE AAMGEVDPAF IQEPEHRPRL AIIEADGIPL IDLTAISSSG
     SADRERIEKL VREVGGACSE WGFFQVVNHG VPAETRGKLE LAARRFFAQD LEEKRKVRRS
     MECTLGYFDT ELTKNVRDWK EVFDVAVSEP TLVPVSSDPE DDRVAEWFNR WPEYPPELRE
     ACEEYGREVE KLAFKLMELI ALSLGLPAER FNSCFKHHQT SLLRLNHYPP CPSPHLALGV
     GRHKDGGAVT VLAQDDVGGL EVRRKSDGEW ILVKPTPDAF IINVGDIIQV WSNDKYESVE
     HRVMVNSERD RFSIPFFLNP AHYTVVKPVD ELINEKNRPK FKPYGWGKFM THRRNSNFKK
     QNDENIQTYH FRVEDFHPRT RAQAQADGSI PLIDLSPVSS TDYSISDRPD PRAIEGLVRE
     IGSACSEWGF FQVKNHGVPS ERRRKLESAA RKLFALPLEE KRKVIRNEES LFGYFDGECG
     DRS
//