ID   A0A2P5CUQ2_PARAD        Unreviewed;       622 AA.
AC   A0A2P5CUQ2;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN   ORFNames=PanWU01x14_122580 {ECO:0000313|EMBL:PON64783.1};
OS   Parasponia andersonii (Sponia andersonii).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Cannabaceae; Parasponia.
OX   NCBI_TaxID=3476 {ECO:0000313|EMBL:PON64783.1, ECO:0000313|Proteomes:UP000237105};
RN   [1] {ECO:0000313|Proteomes:UP000237105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. WU1-14 {ECO:0000313|Proteomes:UP000237105};
RA   Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA   Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA   Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA   Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA   Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA   Smit S., Geurts R.;
RT   "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT   legume Parasponia.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC       known as the alpha DNA polymerase-primase complex) which plays an
CC       essential role in the initiation of DNA synthesis.
CC       {ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC       {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PON64783.1}.
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DR   EMBL; JXTB01000093; PON64783.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P5CUQ2; -.
DR   STRING; 3476.A0A2P5CUQ2; -.
DR   OrthoDB; 49016at2759; -.
DR   Proteomes; UP000237105; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.60; -; 2.
DR   Gene3D; 1.10.8.530; DNA polymerase alpha-primase, subunit B, N-terminal domain; 1.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR043034; DNA_pol_alpha_B_N_sf.
DR   InterPro; IPR016722; DNA_pol_alpha_bsu.
DR   PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR   PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237105}.
FT   DOMAIN          359..570
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   622 AA;  69490 MW;  8629C25ECEBDC737 CRC64;
     MEDEIIAEFN NSGFTLDEDE GEILKKCLAF CINYNLKPSD LVSSWELYYL NRQLNEPTVR
     NAEMDGFLLH LQNEQKESII KEEPGLHLYS SKDVDMILND EDGDEKEVIL GTPTRNSEDL
     YPEQFDYTPQ TNGRTFSSGK PSKLTTPFGQ RTHKFVVKFS INNVPSTEKG HKEQEQENDE
     DGVIKKVQPG RRCTLIVHGS KPETGCRFMY DRIEDRFNAL ESRIKKHVTA FSSSKLYEEP
     VDPTVSSQKS IFTVGMICCD GEGRLNEKST LLQSSVEHSG GQRVRLELQD MNQFSIFPGQ
     IVGIEGHNPS GHCLIASKVV DSIPLSDMLD ANLHPTKKQA LDKEIQSTDL SRTQAELSVI
     IASGPFTTTD NLLFEPLVEL LAYAKRKLPQ LLILLGPFVD SEHPEIEKGT TDRSFDEIFH
     FEILRRLQDY AEYMGSHARV ILVPSIRDAN HDLVFPQPAF DIHPPDLKHQ VTSLTNPGIF
     EANEVKIGCC SVDILKHLSG EEISRNTTGG APSDRMGRLV NHILGQRSFY PLYPPAESIP
     LDFSLAPEAL EISLIPDILI LPSDMKYFAK VLTLGGRGEG EEQVKCICVN PGRLSKGEGG
     GTFVELNYYG NPDTTNASII GI
//