ID A0A2P5D5M9_PARAD Unreviewed; 878 AA.
AC A0A2P5D5M9;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=DNA-directed DNA polymerase {ECO:0000313|EMBL:PON68610.1};
GN ORFNames=PanWU01x14_094190 {ECO:0000313|EMBL:PON68610.1};
OS Parasponia andersonii (Sponia andersonii).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Cannabaceae; Parasponia.
OX NCBI_TaxID=3476 {ECO:0000313|EMBL:PON68610.1, ECO:0000313|Proteomes:UP000237105};
RN [1] {ECO:0000313|Proteomes:UP000237105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. WU1-14 {ECO:0000313|Proteomes:UP000237105};
RA Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA Smit S., Geurts R.;
RT "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT legume Parasponia.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000256|ARBA:ARBA00038341}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON68610.1}.
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DR EMBL; JXTB01000061; PON68610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5D5M9; -.
DR OrthoDB; 6504at2759; -.
DR Proteomes; UP000237105; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.12370; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF0; K(+)_H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW DNA-directed DNA polymerase {ECO:0000313|EMBL:PON68610.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000313|EMBL:PON68610.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000237105};
KW Transferase {ECO:0000313|EMBL:PON68610.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..426
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT REGION 846..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 878 AA; 95104 MW; 8F5BBF679CF25D5B CRC64;
MAVNITSIKT SSNGAWQGDN PLDFAFPLLI VQTTLILVLS RFLAFLLKPL RQPKVIAEIV
GGILLGPSAF GRNKEYLERI FPKWSSPILE SVASIGLLFF LFLVGLELDL SSIRRSGRRA
FGIALAGITL PFVCGIGVAF VLRKAVQGAD QVGYGQFLVF MGVSLSITAF PVLARILAEL
KLLTTRIGET AMAAAAFNDV AAWILLALAV ALAGDGDGGG GKSPLVSVWV LMSGVGFVVF
MLLVVQPAMK WVARQYCSSE VVDEAYICLT LAGVMVSGFV TDLIGIHAIF GAFVFGLTIP
KGGGFADRLI ERIEDFVSGL LLPLYFASSG LKTDVAKISG GKAWGLLVLV ITTACAGKII
GTFVVAMMVK IPARESLALG VLMNTKGLVE LIVLNIGKEK KVLNDEIFAI LVLMALFTTF
ITTPTVMAIY KPSRGGSGGK ESIRTHRKLC DLSISSQEFQ DELRILACVH GPGNVPSLIS
VVESTRSTKK AALKLFIMHL VELTERSSAI VMVQRVRKNG LPFFKRFRRG QWHDRVAGAF
QTYEQLGRVS VSPTTAISPL STMHEDICHA AEEKGVAMII LPFHKQWNGT DKESVENVGH
GWRLVNQRVL KNSPCSVAVL VDRGLSFGGS DIRLTPPGPP NTSVGQRVCV VFFGGPDDRE
CLELGGRMAE HPAVKVTVVR FVNENKEGLE GQGFMLRPSP TKSVEVSYSF STATMNLEKE
KELDETAVAE FKSKWINDDN DQAVGMQVEY IEKVVGESNN NIVEQVLGIG RSGDYDLIIV
GKGRFPSKMV AELADRHAEH PELGPIGDIL ASLEQGMASS VLVIQQHDLA HTEELPVSKV
FPAHKINTNR DQSSSSASTS TTDHQREMEN INDIHNIV
//
