ID A0A2P5EDF9_TREOI Unreviewed; 989 AA.
AC A0A2P5EDF9;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 28-JUN-2023, entry version 19.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|ARBA:ARBA00029784, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|ARBA:ARBA00032199, ECO:0000256|RuleBase:RU366037};
GN ORFNames=TorRG33x02_206240 {ECO:0000313|EMBL:PON83572.1};
OS Trema orientale (Charcoal tree) (Celtis orientalis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Cannabaceae; Trema.
OX NCBI_TaxID=63057 {ECO:0000313|EMBL:PON83572.1, ECO:0000313|Proteomes:UP000237000};
RN [1] {ECO:0000313|Proteomes:UP000237000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. RG33-2 {ECO:0000313|Proteomes:UP000237000};
RA Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA Smit S., Geurts R.;
RT "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT legume Parasponia.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON83572.1}.
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DR EMBL; JXTC01000176; PON83572.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5EDF9; -.
DR STRING; 63057.A0A2P5EDF9; -.
DR InParanoid; A0A2P5EDF9; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000237000; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000237000};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 107..260
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 328..977
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 989 AA; 111771 MW; C117C3D58D3CD0D6 CRC64;
MDDLDKAILI LFDESGAVGS DLKLKAKEYC DKIKEQAAIY RICIERLCFS NLVQVQFWCL
QTLHDVIRVG YSAMSPDERY LIRKSVFSIA CFDGLDDRNV VRVLEGPAFI KNKLAQVLVT
LIYSEYPLVW SSLFVDFLPH LSKGAAVIDM FCRVLNALDV ELISLDYPRT PEELTVGGRV
KDEMRQHCVS QIVRAWFDII SMYRNSDQEL CTSVLESMRR YVSWIDIGLI VNDVFISLLF
ELVLVDGLSE QLRGAAAGCL LAVVSKRMDH QTKLSLLQSL RISRVFGLVN KDGDSDLISS
LAALLTGYAV EVLECFKRLN SEDSKGISME LLDEVLPSVF YVMQHCELDT TFNIVQFLSG
YVATMKSLSP LREKQLLHVG QILEVIRSQI LYDPMYRDNL DVLDKIGREE EDRMVEFRKD
LFVLLRCVGR VAPDVAHLFI QNSLVSAVAS PSDRNVEEVE AALSLLYAFG ESMSEEAMRT
GSGLLSELVP MLLSTRLSCH SNRLVALVYL ETITRYLKFV QENTQYIPLV LSAFLDERGI
HHPSINVSRR ASYLFMRVVK LLKVKLVPFI ERILQSLQDT VARFTSMNCT SKELLGSEDG
SHIFEAIGLL IGMEDVPPAK QSDYLSSLLT PLCQQVEALI MNAKVLTPEE TPVKVTNVQQ
IIIAINSLSK GFSERLVTAS RPAIGLMFKQ TLDVLLQVLI VFPKIEPLRS RVTSFIHRMV
ETLGASVFPY LPKALEQLLS ESEPKEMVGL LLLLNQLICK FSTLVHDILD EVFPTIAGRI
LSVIPRDVFP SGPGTNTEEI RELQELQRIL YTFLHVIATH DLSSIFLSPK SRGYLHPIMQ
LLLFTACKHK EILVRKACVQ ILIRLIKDWC AKPLAEEKVP GFQSFIIENF ATHCCLYSVL
DRSFEFRDAN TLVLFGEIVL AQKVMYEKFG DDFLVHFVSK GLSAAHCPQD LAEQYCQKLQ
GTDIKGLKSF YQSLVENLRV QQNGSLVFR
//
