ID A0A2P5EMW1_TREOI Unreviewed; 1869 AA.
AC A0A2P5EMW1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ABC transporter A, ABCA {ECO:0000313|EMBL:PON86894.1};
GN ORFNames=TorRG33x02_172780 {ECO:0000313|EMBL:PON86894.1};
OS Trema orientale (Charcoal tree) (Celtis orientalis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Cannabaceae; Trema.
OX NCBI_TaxID=63057 {ECO:0000313|EMBL:PON86894.1, ECO:0000313|Proteomes:UP000237000};
RN [1] {ECO:0000313|Proteomes:UP000237000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. RG33-2 {ECO:0000313|Proteomes:UP000237000};
RA Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA Smit S., Geurts R.;
RT "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT legume Parasponia.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCA family.
CC CPR flippase (TC 3.A.1.211) subfamily. {ECO:0000256|ARBA:ARBA00008526}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PON86894.1}.
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DR EMBL; JXTC01000124; PON86894.1; -; Genomic_DNA.
DR STRING; 63057.A0A2P5EMW1; -.
DR InParanoid; A0A2P5EMW1; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000237000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF263; ABC TRANSPORTER A FAMILY MEMBER 1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000237000};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 976..995
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1171..1194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1228..1247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1259..1277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1289..1308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1320..1339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1359..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 542..775
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1441..1679
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1869 AA; 208816 MW; 9A98D863072D0C2A CRC64;
MLRKSWLLKA RHPFITAAEI LLPTVVMLLL IAVRTRVDTQ IHPAQPYIRK DMFVEVGSGM
SPSFEQVLEL LWSKGECLAF APDTEKTKTM INLMSIKFPL LQLVSRVYKD EQELETYIRS
DDYGICSQIR NCSNPKIKGA VVFHDQGPQL FDYSIRLNHT WAFSGFPDVK SIMDTNGPYL
NDLELGINPV PIMQYSFSGF LTLQQILDSF IIFAAQQSDS GNIEPSLHSF GESSSLKVPL
MQYSPSNIRI VPFPTREYTD DEFQSIVKKV MGVLYLLGFL YPISRLISYT VFEKEQKIKE
GLYMMGLKDE IFYLSWFIVY SLQFAVSSAI IVICTMDNLF KYSDKSVVFI YFFLFGLSAI
TLSFLISTFF SRAKTAVAVG TLSFLGAFFP YYSVNDEAVS MILKVVASLL SPTAFALGSV
NFADYERAHV GLRWTNMWRP SSGVNFSVCL LMMLVDTMLY GAIGLYLDKV LPRENGIRYP
WNFIFKKWFW KKKKMSKDHT STLEVNVNQK ALENFSRTEN FQPAVEAISL DMKQHELDGR
CIQIRNLHKV YDSKRGKCCA VNSLQLTLYE NQILALLGHN GAGKSTTISM LVGLVPPTSG
DALVFRQNII SDMDEIRKGL GVCPQNDILF PELTVREHLE IFAILKGVEE DSMERVVTDM
VDQVGLADKS NTVVKALSGG MKRKLSLGIA LIGNSKVIIL DEPTSGMDPY SMRLTWQLIK
KIKKGRIILL TTHSMDEADE LGDRIAIMAN GSLKCCGSSL FLKHQYGVGY TLTLVKSAPS
ASVAADIVYR HIPSATCVSE VGTEISFKLP LASSLSFESM FREIERCMRR SDCNSKANDG
EEKDYPMIES YGISVTTLEE VFLRVAGCDY NEAEFLEQKN SIYSPCPVTS QVSHESAPKM
ILHSDKLFGN YKNILRFICT VVGKACGLIF ATVLSFINFL TRQCCSCCFI SRSTFWQHCK
ALFIKRAISA RRDQKTIVFQ LLIPVVFLLV GLLFLKLKPH PDQQSVNFTT SNFNTLLSGG
GGGGPIPFDL SSPIAKEVSQ YIEGGWIQVF KPSAYKFPDS EKALTDAIEA AGPTLGPVLL
SMSEYLMSSF NESYQSRYGA VVMDDQNDDG SLGYTILHNS SCQHAAPTYI NVMNAAILRL
ATHDKNMTIQ TRNHPLPMTK SQHLQRHDLD AFSAAVIVSI AFSFIPASFA VSIVKEREVK
AKHQQLISGV SVLSYWASTY IWDFVSFLFP FSFAIALFNI FGLDQFIGKD CFLPTVIMFL
EYGLAVASST YCLSFFFSDH TMAQNVVLLI NFFTGLILMV ISFIMGLIKT TASANSFLKN
FFRLSPGFCF ADGLASLALL RQGMKDKSSD AAFDWNVTGA SICYLGVESI CYFLLTLGLE
ILPSYKEWWS IRSFQRDGSS PYLEPLLRSS TETVALDFDE DIDVKTERNR VLSGSIENAI
IYLRNLRKVY PGGKYRNEKV AVHSLTFSVQ EGECFGFLGT NGAGKTTTLS MLSGEESPTD
GTAYIFGKDI CSNPKAARRH IGFCPQFDAL LEYLTVQEHL ELYARIKGVS DHQIDDVVME
KLTEFDLLKH ANKPSFSLSG GNKRKLSVAI AMIGDPPIVI LDEPSTGMDP IAKRFMWEVI
SRISTRRGKT AVILTTHSMD EAQALCTRMG IMVGGRLRCI GSPQHLKTRF GNHLELEIKP
VEVSCTEMEN LCQSIQERLV NISLHSRSLL GDLEACIGRT DFITSESTSR AEISLSREMI
TMIGRWLGNE ERIKMLISSI PVPDGVLGEQ LCEQMIRDGG IPLSIFSEWW LSKDKFSAID
SFVLSSFPGA TFQGCNGLSV QYQLPYGEGL SLADVFGHLE RNRNGLGIAE YSLSQSNLET
IFNHFAANP
//
