ID   A0A2P5FWA8_TREOI        Unreviewed;       372 AA.
AC   A0A2P5FWA8;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=NAD(P)-binding domain containing protein {ECO:0000313|EMBL:POO02047.1};
GN   ORFNames=TorRG33x02_018310 {ECO:0000313|EMBL:POO02047.1};
OS   Trema orientale (Charcoal tree) (Celtis orientalis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Cannabaceae; Trema.
OX   NCBI_TaxID=63057 {ECO:0000313|EMBL:POO02047.1, ECO:0000313|Proteomes:UP000237000};
RN   [1] {ECO:0000313|Proteomes:UP000237000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. RG33-2 {ECO:0000313|Proteomes:UP000237000};
RA   Van Velzen R., Holmer R., Bu F., Rutten L., Van Zeijl A., Liu W.,
RA   Santuari L., Cao Q., Sharma T., Shen D., Roswanjaya Y., Wardhani T.,
RA   Kalhor M.S., Jansen J., Van den Hoogen J., Gungor B., Hartog M.,
RA   Hontelez J., Verver J., Yang W.-C., Schijlen E., Repin R., Schilthuizen M.,
RA   Schranz E., Heidstra R., Miyata K., Fedorova E., Kohlen W., Bisseling T.,
RA   Smit S., Geurts R.;
RT   "Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-
RT   legume Parasponia.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POO02047.1}.
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DR   EMBL; JXTC01000005; POO02047.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P5FWA8; -.
DR   STRING; 63057.A0A2P5FWA8; -.
DR   InParanoid; A0A2P5FWA8; -.
DR   OrthoDB; 23at2759; -.
DR   Proteomes; UP000237000; Unassembled WGS sequence.
DR   GO; GO:0047918; F:GDP-mannose 3,5-epimerase activity; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd05273; GME-like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR033890; GDP-Man_epi.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR   PANTHER; PTHR43574:SF13; GDP-MANNOSE 3,5-EPIMERASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000237000}.
FT   DOMAIN          26..265
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   372 AA;  42043 MW;  8EF30B26392D0FAE CRC64;
     MGSAYGEYTY ENLEREPYWP SEKLRISITG AGGFIASHIA RRLKSEGHYI IASDWKKNEH
     MTEDMFCHEF HLVDLRVMDN CLKVTNGVDH VFNLAADMGG MGFIQSNHSV IMYNNTMISF
     NVLEAARING VKRFFYASSA CIYPEFKQLD TNVSLKESDA WPAEPQDAYG LEKLATEELC
     KHYNKDFGIE CRIGRFHNIY GPFGTWKGGR EKAPAAFCRK AITSTHKFEM WGDGLQTRSF
     TFIDECVEGV LRLTKSDFRE PVNIGSDEMV SMNEMAEIVL SFENKNLPIH HIPGPEGVRG
     RNSDNTLIKE KLGWSPTMKL KDGLRVTYFW IKEQIEKEKG EGVDLSVYGS SKVVGTQAPV
     QLGSLRAADG KE
//