ID A0A2P5I0G0_9PEZI Unreviewed; 1342 AA.
AC A0A2P5I0G0;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN ORFNames=DHEL01_v205619 {ECO:0000313|EMBL:POS75977.1};
OS Diaporthe helianthi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Diaporthaceae; Diaporthe.
OX NCBI_TaxID=158607 {ECO:0000313|EMBL:POS75977.1, ECO:0000313|Proteomes:UP000094444};
RN [1] {ECO:0000313|EMBL:POS75977.1, ECO:0000313|Proteomes:UP000094444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7/96 {ECO:0000313|EMBL:POS75977.1,
RC ECO:0000313|Proteomes:UP000094444};
RA Baroncelli R.;
RT "Polyketide synthases of a Diaporthe helianthi virulent isolate.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS75977.1}.
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DR EMBL; MAVT02000420; POS75977.1; -; Genomic_DNA.
DR STRING; 158607.A0A2P5I0G0; -.
DR InParanoid; A0A2P5I0G0; -.
DR OrthoDB; 22721at2759; -.
DR Proteomes; UP000094444; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd00030; C2; 1.
DR CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000094444}.
FT DOMAIN 786..1021
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1177..1225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1235..1254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1342 AA; 148203 MW; 51509F02747F39CC CRC64;
MDARRMSPDG SSRPPPRPRR PSASLSSVPL QRTFDPASGG APVLGTVPRR TSAGNLRSTT
YRPGNPTGAQ ATVRAVTPEP TEHGTQEPTG TNNYGEPGTP VPGTAVNHPI GPASPRSSSP
RSIPNVPGSV MSSSSSTARR QGVVFNDHFP SSLDSASSSP PARPQIRPRG HTLDGPYRQP
SAAPTPESSR HRVGSVSSSG SMGSMPPHED ALRGPPVPRH SPAIESAGYP SVYPARPTDL
HIHTGVTTKE KKGLTRAKLM KRISRPTSPM MSPPPSVDSL PLPVPTDDAN KVLLLMKTLC
GRMRGEVSYQ NEANGQWHSG LCYIEEEKGS LMFDSGEHGP FHTSVISDLR GCRVLPVHKP
SLDRPCLEIV NSHSGVEVLL WPHVAEELDL WLAALLCWQQ VRPSAMRVNS PSTTPTSQYR
PELMRRGSST PSNSGTIIKV SRVSIWDKGA AYSPRAIVKR TSTRDLRSPQ TGWRKVSCIL
SDNGELKLIS ENDVTVLCII SLSQLSRCAI QQLDKSVLDE DYCISIFPMY SSTSTQLSIF
RPVYISLDHR VLFEVWFVLL RAFTVPEIYA LDTENDDQVL EVTDFDADLP FQMFRVEKTI
NLRVIEAKVG GPTSPHTASR DRHGRNHDDA FVGNYFAEVM LDGDVRARTI TKTDTRNPFW
RDDCEFADLP ANLPYLSVIL KRIDGNLESM AHQLQASLGL PRTGNLTEVA CGSVDIPLTQ
LERGKDHEQW LQIYDERQQS IGTMLCKVRH EEVVVFLARD YQPLSEMLHK FSSGLTAQIS
EALPGQLRRL AEIFLNVFQV STTASDWLMA LVEDEIDGIG QQSQMRKMRF SRRLKSSENL
DVSNPYEREA LRDMGKSLAG EANLLFRGNS LLTQALEFHM RRLGTEYIEE ILGDKIFEVN
EINPNCEVDP GKLQQGEDIG QHWDQLLQFT NEIWDCIAKS ANKFPPELRH ILKYIRAVAE
DRYGDFLRTV AFTSVSGFLF LRFICPAILN PKLFGLLRDY PRPRAQRTLT LIAKALQALA
NLSNIGKKEV WMDPMNRFLS SRRQALKDFI DEICAIPAER SNCILPASYS TPITILGRLS
PLAREGFPSL PYLIDHARSF ALLVRLWVDN QPLSGDAENQ YDGELLKFHR LCVGLQQRAD
VCMARIDSIR AADIDDFSQR TDSDGALADA IEHVGLAESM NTSHKPGSST SWVDRDRPPG
SSDGSSLDDT RGQGLHSHRS SERWASGLRQ AVGSAGELSD RKYHHGSMKS LRSGKNARKF
LSGFLRKVDR TDSPEASGSS GSPSASPWQN GSGDNSIGSA YKSGSGSTTP TGTLKSRDKE
KGRSTFGGLA EAWKEFDPSS RH
//
