ID A0A2P5WF46_GOSBA Unreviewed; 394 AA.
AC A0A2P5WF46;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=GOBAR_AA30984 {ECO:0000313|EMBL:PPR89707.1};
OS Gossypium barbadense (Sea-island cotton) (Egyptian cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3634 {ECO:0000313|EMBL:PPR89707.1, ECO:0000313|Proteomes:UP000239757};
RN [1] {ECO:0000313|EMBL:PPR89707.1, ECO:0000313|Proteomes:UP000239757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Xinhai21 {ECO:0000313|Proteomes:UP000239757};
RC TISSUE=Leaf {ECO:0000313|EMBL:PPR89707.1};
RA Chen X., Liu X., Zhao B., Zheng H., Hu Y., Lu G., Yang C., Chen J.,
RA Shan C., Zhang L., Zhou Y., Wang L., Guo W., Bai Y., Ruan J., Shangguan X.,
RA Mao Y., Jiang J., Zhu Y., Lei J., Kang H., Chen S., He X., Wang R.,
RA Wang Y., Chen J., Wang L., Yu S., Wang B., Wei J., Song S., Lu X., Gao Z.,
RA Gu W., Deng X., Ma D., Wang S., Liang W., Fang L., Cai C., Zhu X., Zhou B.,
RA Zhang Y., Chen Z., Xu S., Zhu R., Wang S., Zhang T., Zhao G.;
RT "Genome of allotetraploid Gossypium barbadense reveals genomic plasticity
RT and fiber elongation in cotton evolution.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family. {ECO:0000256|ARBA:ARBA00006702,
CC ECO:0000256|RuleBase:RU003465}.
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DR EMBL; KZ667856; PPR89707.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5WF46; -.
DR Proteomes; UP000239757; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF86; PROTEIN-SERINE_THREONINE PHOSPHATASE; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000239757}.
FT DOMAIN 138..390
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 38..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 42173 MW; 007E25230B13ECF5 CRC64;
MSCSVAVSNS PAFSPSSSLF LNKTPIISPS TEALNLTLTH LKTSSSPASP SPSPSSPFRL
RLPKPPPVSL LSSSSASNSS PSSGSGSAPG LGSGPVSTVL KRKRPARLEI PVVTEAMGLG
IPATPCEVGK ELEREGDGYS VYCKRGRREA MEDRFSASVE LQGDSKKAIF GIFDGHGGAK
AAEFAAQKLE KNILDQVITR RDNTAVMDAV KQGYLKTDAE FFKEDNAGGT CCLTALIQNG
DLVVSNAGDC RAVLSRGGRA EPLTSDHRPS REDERSRIQN LGGYVDLCRG VWRIQSSLAV
SRGIGDRHLK QWVIAEPETK IVSIEPDCEF LILASDGLWD KVSDQEAVDI ARPSFIGTDK
PNLLFACKKL VDLSVSRGSF DDISVMLVHL GYYI
//
