ID A0A2P5XQI9_GOSBA Unreviewed; 449 AA.
AC A0A2P5XQI9;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=GOBAR_AA15057 {ECO:0000313|EMBL:PPS05591.1};
OS Gossypium barbadense (Sea-island cotton) (Egyptian cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3634 {ECO:0000313|EMBL:PPS05591.1, ECO:0000313|Proteomes:UP000239757};
RN [1] {ECO:0000313|EMBL:PPS05591.1, ECO:0000313|Proteomes:UP000239757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Xinhai21 {ECO:0000313|Proteomes:UP000239757};
RC TISSUE=Leaf {ECO:0000313|EMBL:PPS05591.1};
RA Chen X., Liu X., Zhao B., Zheng H., Hu Y., Lu G., Yang C., Chen J.,
RA Shan C., Zhang L., Zhou Y., Wang L., Guo W., Bai Y., Ruan J., Shangguan X.,
RA Mao Y., Jiang J., Zhu Y., Lei J., Kang H., Chen S., He X., Wang R.,
RA Wang Y., Chen J., Wang L., Yu S., Wang B., Wei J., Song S., Lu X., Gao Z.,
RA Gu W., Deng X., Ma D., Wang S., Liang W., Fang L., Cai C., Zhu X., Zhou B.,
RA Zhang Y., Chen Z., Xu S., Zhu R., Wang S., Zhang T., Zhao G.;
RT "Genome of allotetraploid Gossypium barbadense reveals genomic plasticity
RT and fiber elongation in cotton evolution.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
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DR EMBL; KZ664429; PPS05591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P5XQI9; -.
DR Proteomes; UP000239757; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942:SF69; MLO-LIKE PROTEIN; 1.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR Pfam; PF03094; Mlo; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000239757};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 449 AA; 51614 MW; DCEB5BC8174601B6 CRC64;
METVESISLY YKPTWVVAAV CFVIILISLF AERGLNYLGK CLTHSNQDAL FEALQKLKAE
LMLLGFISLL LNVFQGLISQ ICIPSHFEST MLPCKKHTEI KGHENYSPPA INNERHLLSE
KSGNFSDHCS LQGKVPLLST ESFHELHILI FVVAIVHVVS CAVILVLGRA RIRQWKPWED
SISTVPAGPA KVTHRHHLNN VLKKLAWGYW RRAAVISWII SFFKQFYSSV TMSEYIALRE
GFIMTNCLSH QEFDFHKDMV ESLERDFRHV VGISWYQWLF AVVFLALNVE VDQLNWFGEW
ESPDLTIIEV NGVLQLLLLV GAKLEHIIVR LAQDVDVMKK HPGQESAWVR PSDEYFWFNR
PRLLLDFIHF ILFQNAFEIA FFFWILWTYG FHSCMMEKKG YIITRLIIGV IVQVLCSYIT
LPLYALVTKM GTASMAESVS VPMQSPGII
//
