ID A0A2P6PUP0_ROSCH Unreviewed; 424 AA.
AC A0A2P6PUP0;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN ORFNames=RchiOBHm_Chr6g0285851 {ECO:0000313|EMBL:PRQ25643.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ25643.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ25643.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate +
CC CO2 + H2O + NADP(+); Xref=Rhea:RHEA:34331, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:17640, ChEBI:CHEBI:30854, ChEBI:CHEBI:57783,
CC ChEBI:CHEBI:58349; EC=1.14.13.168;
CC Evidence={ECO:0000256|ARBA:ARBA00035920};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU361177};
CC -!- PATHWAY: Plant hormone metabolism; auxin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004814}.
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|RuleBase:RU361177}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ25643.1}.
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DR EMBL; PDCK01000044; PRQ25643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6PUP0; -.
DR STRING; 74649.A0A2P6PUP0; -.
DR EnsemblPlants; PRQ25643; PRQ25643; RchiOBHm_Chr6g0285851.
DR Gramene; PRQ25643; PRQ25643; RchiOBHm_Chr6g0285851.
DR OMA; NTMGKTP; -.
DR OrthoDB; 5488474at2759; -.
DR Proteomes; UP000238479; Chromosome 6.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0103075; F:indole-3-pyruvate monooxygenase activity; IEA:RHEA.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR PANTHER; PTHR43539:SF11; INDOLE-3-PYRUVATE MONOOXYGENASE YUCCA8-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Auxin biosynthesis {ECO:0000256|ARBA:ARBA00023070};
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU361177};
KW Monooxygenase {ECO:0000256|RuleBase:RU361177, ECO:0000313|EMBL:PRQ25643.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU361177}; Pyruvate {ECO:0000313|EMBL:PRQ25643.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479}.
SQ SEQUENCE 424 AA; 47289 MW; 4967176FC849A381 CRC64;
MENLFRLVDH EDFFARRCIM VNGPVIVGAG PSGLATAACL RDQGVPFEVL ERAECIASLW
QKRTYDRLKL HLPKAFCQLP KLPFPQDFPE YPTKRQFIDY LESYAKHFEI NPKFNSSVQS
ARYDETSGFW RVKTVSTTGS TRSEVEYICR WLIVATGENA ECVVPDIDGL SEFGGEVVHA
CEYKSGEKYK GQKVLVVGCG NSGMELSLDL CNHNASPSMV VRSSVHVLPR EIYGKSTFEL
AVFLLKWLPV WLADKLLLLL SWLILGSIEK YGLNRPSVGP LELKNTQGKT PVLDIGALDK
IKSGGIKVVP GIKRFSYGRV ELVDGEVLDI DSVVLATGYR SNVPSWLQEG EFFSKNGFPK
QPFPQGWKGN AGLYAVGFTR RGLSGASCDA MRIAQDIGNV WKCETKQNKK RTTAGHRRCI
SQTF
//
