ID A0A2P6QC48_ROSCH Unreviewed; 990 AA.
AC A0A2P6QC48;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146};
DE EC=7.2.2.10 {ECO:0000256|RuleBase:RU361146};
GN ORFNames=RchiOBHm_Chr5g0039001 {ECO:0000313|EMBL:PRQ31758.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ31758.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ31758.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- FUNCTION: Catalyzes the hydrolysis of ATP coupled with the transport of
CC calcium. {ECO:0000256|RuleBase:RU361146}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate;
CC Xref=Rhea:RHEA:18105, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29108, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:456216; EC=7.2.2.10;
CC Evidence={ECO:0000256|ARBA:ARBA00000363,
CC ECO:0000256|RuleBase:RU361146};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361146}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU361146}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IIB subfamily. {ECO:0000256|ARBA:ARBA00006124,
CC ECO:0000256|RuleBase:RU361146}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361146}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ31758.1}.
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DR EMBL; PDCK01000043; PRQ31758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6QC48; -.
DR STRING; 74649.A0A2P6QC48; -.
DR EnsemblPlants; PRQ31758; PRQ31758; RchiOBHm_Chr5g0039001.
DR Gramene; PRQ31758; PRQ31758; RchiOBHm_Chr5g0039001.
DR OrthoDB; 4225021at2759; -.
DR Proteomes; UP000238479; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006408; P-type_ATPase_IIB.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01517; ATPase-IIB_Ca; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR PANTHER; PTHR24093:SF434; CALCIUM-TRANSPORTING ATPASE 13, PLASMA MEMBRANE-TYPE-RELATED; 1.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU361146};
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU361146};
KW Calcium transport {ECO:0000256|RuleBase:RU361146};
KW Hydrolase {ECO:0000313|EMBL:PRQ31758.1};
KW Ion transport {ECO:0000256|RuleBase:RU361146};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361146};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU361146};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361146};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361146}; Transport {ECO:0000256|RuleBase:RU361146}.
FT TRANSMEM 311..332
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361146"
FT TRANSMEM 355..388
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361146"
FT TRANSMEM 921..941
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361146"
FT TRANSMEM 953..971
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361146"
FT DOMAIN 804..973
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
SQ SEQUENCE 990 AA; 108955 MW; 2C9A5A4510111C88 CRC64;
MSDSPTMHMH AESMLDDPST RLLNDKPKNK WRIAVSTIFC IRALLSLLNQ ITKTNFITSS
SPVSSNSTFN VDQIALTRLV KNKDLAQLQE LGGVEGVALH LKSDKEHGIH CHDAEDIPDR
IKEFGSNVYI KDPTVLILLG CAALSLGFGI NEHGFKEGCT NGGTILLAVI QIISVSAVSD
YRQSRPLVRN NIQIEAWRGG RRQKIYVYET VVGDVILLNI GDRVPADGLL VQGHSLQVDE
SSMTGTDSPV EISHHQNPFL FSGTKITHGY GRMLVTSVGM NTTWGEMMSQ MRQDTSERTP
MQERLEKLNS LIGKVALLLA FLLLVVLLVR YFTGNTKDEN GNKEFNGSNT EVDDIISAVI
GIVAAAISIV VVAIPEGLSL ALILAVAYSK KIMMADKAMD LKLSACETMG SVTTICTDKT
GTLTMNQMEV TQFWLGKYSL EEEAYSSEIS PSVLHLIQEG VALNTTGSVH KQSLDSKVEI
SGSPTEKAII SWGVFKLQMD MEKVMKSCSI LHVEAFDSQN MRSGVSMKRN ADNTVHVHWK
GAAEIILEMC SSYYNPSGLV IDMGDSEKMS FEEIIQGMAA SRLRCIAFAH KEVPADQNHR
TMLKEDGLTL VGLVGLKDPC CPEAKKAVED CQYAGVMVKM ITGDNIFTAK AIATECGILK
SSDDIFSGAV INGVEFQSYT DLERMLKLDN ICVMARSSAA DKLLMVRCLK QKGHVVAVTG
HGATDAPALE EADIGLSMGI QGTEVAKESS DIIITDDNFA SVVSVLACGR CVYHNTQKLV
QFQLTSNVAG LLINFAVAAS SRQVPFTIVR SIWLNMIMDT LLALALTKDK PTKELMEKPP
VGRTEPFITN VMCRNLLAQA LYQTTVLLIL QFRGEAMFGV NDKVNGTLIF NTFVFCQMFN
EFNARKLVKK DIFRNIHTDK LFMGIIAVAV ILQIVTVEFL SKFEDIERLN YRLWGVCLGI
AAISWPIGWA VKCIPVPQKP IFHYLKMKMH
//
