ID A0A2P6QIC4_ROSCH Unreviewed; 103 AA.
AC A0A2P6QIC4;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 28-JUN-2023, entry version 25.
DE RecName: Full=Histone H4 {ECO:0000256|RuleBase:RU000528};
GN ORFNames=RchiOBHm_Chr1g0364991 {ECO:0000313|EMBL:PRQ58966.1},
GN RchiOBHm_Chr3g0467051 {ECO:0000313|EMBL:PRQ43303.1},
GN RchiOBHm_Chr5g0062221 {ECO:0000313|EMBL:PRQ33852.1},
GN RchiOBHm_Chr5g0063251 {ECO:0000313|EMBL:PRQ33936.1},
GN RchiOBHm_Chr5g0063281 {ECO:0000313|EMBL:PRQ33939.1},
GN RchiOBHm_Chr5g0063731 {ECO:0000313|EMBL:PRQ33980.1},
GN RchiOBHm_Chr7g0187711 {ECO:0000313|EMBL:PRQ16758.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ33936.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ33936.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H4 family.
CC {ECO:0000256|ARBA:ARBA00006564, ECO:0000256|RuleBase:RU000528}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ33936.1}.
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DR EMBL; PDCK01000045; PRQ16758.1; -; Genomic_DNA.
DR EMBL; PDCK01000043; PRQ33852.1; -; Genomic_DNA.
DR EMBL; PDCK01000043; PRQ33936.1; -; Genomic_DNA.
DR EMBL; PDCK01000043; PRQ33939.1; -; Genomic_DNA.
DR EMBL; PDCK01000043; PRQ33980.1; -; Genomic_DNA.
DR EMBL; PDCK01000041; PRQ43303.1; -; Genomic_DNA.
DR EMBL; PDCK01000039; PRQ58966.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6QIC4; -.
DR SMR; A0A2P6QIC4; -.
DR STRING; 74649.A0A2P6QIC4; -.
DR EnsemblPlants; PRQ16758; PRQ16758; RchiOBHm_Chr7g0187711.
DR EnsemblPlants; PRQ33852; PRQ33852; RchiOBHm_Chr5g0062221.
DR EnsemblPlants; PRQ33936; PRQ33936; RchiOBHm_Chr5g0063251.
DR EnsemblPlants; PRQ33939; PRQ33939; RchiOBHm_Chr5g0063281.
DR EnsemblPlants; PRQ33980; PRQ33980; RchiOBHm_Chr5g0063731.
DR EnsemblPlants; PRQ43303; PRQ43303; RchiOBHm_Chr3g0467051.
DR EnsemblPlants; PRQ58966; PRQ58966; RchiOBHm_Chr1g0364991.
DR Gramene; PRQ16758; PRQ16758; RchiOBHm_Chr7g0187711.
DR Gramene; PRQ33852; PRQ33852; RchiOBHm_Chr5g0062221.
DR Gramene; PRQ33936; PRQ33936; RchiOBHm_Chr5g0063251.
DR Gramene; PRQ33939; PRQ33939; RchiOBHm_Chr5g0063281.
DR Gramene; PRQ33980; PRQ33980; RchiOBHm_Chr5g0063731.
DR Gramene; PRQ43303; PRQ43303; RchiOBHm_Chr3g0467051.
DR Gramene; PRQ58966; PRQ58966; RchiOBHm_Chr1g0364991.
DR OMA; RRNRNMS; -.
DR OrthoDB; 828845at2759; -.
DR Proteomes; UP000238479; Chromosome 1.
DR Proteomes; UP000238479; Chromosome 3.
DR Proteomes; UP000238479; Chromosome 5.
DR Proteomes; UP000238479; Chromosome 7.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR CDD; cd00076; H4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR019809; Histone_H4_CS.
DR PANTHER; PTHR10484; HISTONE H4; 1.
DR PANTHER; PTHR10484:SF0; HISTONE H4; 1.
DR Pfam; PF15511; CENP-T_C; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00047; HISTONE_H4; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU000528};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000528};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU000528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000528};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479}.
FT DOMAIN 39..96
FT /note="CENP-T/Histone H4 histone fold"
FT /evidence="ECO:0000259|Pfam:PF15511"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 11409 MW; A9FD57725A2A7598 CRC64;
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK
IFLENVIRDA VTYTEHARRK TVTAMDVVYA LKRQGRTLYG FGG
//
