ID A0A2P6QW77_ROSCH Unreviewed; 1465 AA.
AC A0A2P6QW77;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Putative TIR domain, P-loop containing nucleoside triphosphate hydrolase {ECO:0000313|EMBL:PRQ38435.1};
GN ORFNames=RchiOBHm_Chr4g0413891 {ECO:0000313|EMBL:PRQ38435.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ38435.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ38435.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ38435.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PDCK01000042; PRQ38435.1; -; Genomic_DNA.
DR EnsemblPlants; PRQ38435; PRQ38435; RchiOBHm_Chr4g0413891.
DR Gramene; PRQ38435; PRQ38435; RchiOBHm_Chr4g0413891.
DR OMA; ELRIWCC; -.
DR OrthoDB; 1132279at2759; -.
DR Proteomes; UP000238479; Chromosome 4.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF585; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PRQ38435.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 11..177
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1404..1439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1439
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1465 AA; 163870 MW; BFC522086A0D20DD CRC64;
MVIIEEATHP WTYDVFLSFR GEDTRNNFTG HLCRALRQNG INTFMDDQLK RGEEISPALL
QAIEESKISI IVFSKDYASS KWCLDELVKI LECKKSNQQE VRPVFYKVNP SDIRKHRGSF
GEALANHECK FEDNLDKVQK WKAALKEAAD LSGWPLSEHC SESSVIHKIV EEILEQVINS
TYLYVAKYPV GIEPRVQEIH NLLGVGERDV RMVGIWGGGG IGKTTIARAV YNSFAHKFDG
SCFLEDVREN SMGAEGFVKL QTKLLCEILK GTNLKVANVA RGITMIKKML QYKSVLLVLD
DVNDIDQLNN LAGDCSWFGK GSRIIIATRD EQLLTDHGVE LIYKVQELDH HEALELFSWN
AFKRNGPLDG FVELTERAIY YARGLPLVLC VLGSYICGGN VEQWEAALDG FKSSKIQDVL
KISYNGLDHR VKEAFLDIAC FFKGENRKHV IKILEACGSK QHVINVLIKK ALISIDYKDC
IWMHDLVEEM GRDIVHELSP NNPGKRSRLW FHEDVYHVLT ENIGTAKVIG IKVQFPKDSD
VIYLSGTTFS NMPNLRLFIY RSGRYAGVVD NLPNSLRVLD WPDCDLQFLP SNSFAVINMP
RSCIRGLEVG YKHLKNLTSV NLKHCKYLTK VSDLSGSPNL QRLDLSYCQN LVEVHRSVGF
LNKLDYLNLW FCSSLKTFPT EVSWKSMRTL QLVYCERLEN FLNIVHKMES IKTLTLNGSG
IKELHSCIGR CTTLEALDLQ YGTSIKQLPS SIGNLTSLVK LDASGSPLKE LPSSIGNLTS
LTELKLSKTL IQELPSSIGK LSSLVELDAS GTLVEELPSS IGHLTSLREL QLSKTPIKEL
PSSIGKLSSL VKLDASETLI EELPSSIEHL TSLRELKLSK TPIKGLPSSI ENLTSLVELD
VCETLIEELP PSIGRLTSLE TLKLSKTLIK ELPSLIGYLN SLRVLEASET LIEELPSSIK
KLTSLFRLDL SKTPIKELPS SIWNLTSLTN LDASETMIEE LPSSIENLFG LKLKGCANLR
TVPHSVYGGL QHLEELDLSW CPKLVTFPSR ASALVSSSAE SLPPMLPTNS NNGHDHPGSS
LFPKLRWLYF KGCKLSVSDF LTNLDCASTL RTLNLSRSSF DSLPACISKF HRLDDLDLSG
CERLRDISEL PPNIAYINLD DCVSLERFSK LSNILEQKDT PGLLRIMHLS NCNRLMDNLG
MDMVSKMAKA LLNQLVCHGF GWPVNCWMLR LPSLPGIEVP KWFNRGEGAT SVPPGSPYPE
YDICEILIKI PRNLMGERIR LVVCVVLEIT QDFSGECGVT VVINKQGHYG GGDYGLSSAH
DDVYVCLTCI DFMELAVVDH EVRVTFEGYN SRGKRLLLKS FGVHLANMQE NDDDQVSGEY
SARERYRQSN ASISDFENEE GAAVASLVSD DSSSGEVDDD HHDGEQEQEQ EPHPPTERFE
DLTRQTNIGR AMLAFLRCFG ITTCL
//
