ID A0A2P6R6N1_ROSCH Unreviewed; 1248 AA.
AC A0A2P6R6N1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative RNA-directed DNA polymerase {ECO:0000313|EMBL:PRQ42072.1};
DE EC=2.7.7.49 {ECO:0000313|EMBL:PRQ42072.1};
GN ORFNames=RchiOBHm_Chr3g0453641 {ECO:0000313|EMBL:PRQ42072.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ42072.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ42072.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ42072.1}.
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DR EMBL; PDCK01000041; PRQ42072.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6R6N1; -.
DR EnsemblPlants; PRQ42072; PRQ42072; RchiOBHm_Chr3g0453641.
DR Gramene; PRQ42072; PRQ42072; RchiOBHm_Chr3g0453641.
DR OMA; DNITQIR; -.
DR Proteomes; UP000238479; Chromosome 3.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd06222; RNase_H_like; 1.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR026960; RVT-Znf.
DR PANTHER; PTHR46890; NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR46890:SF45; RNA BINDING _ RNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF13966; zf-RVT; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:PRQ42072.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:PRQ42072.1};
KW Transferase {ECO:0000313|EMBL:PRQ42072.1}.
FT DOMAIN 351..630
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1085..1215
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 1248 AA; 140936 MW; A37B47D7DFB62EA5 CRC64;
MVIGDFNAVL GAHEKSGGPS PSRLSCADFQ SMSDTCDFVH LDTSGLFFTW SNGWSTSGHV
ELRLDRCLCD TTWFEAWPFT SCVALPRVVS DHSPLIFSAS KLSPSGPKPF RFQSMWLQHP
NFHAVVSNCW NSFQLCGCPM FVTLQKLKAL KHCLRDWNKA VFGNVHQKVV AARENLVNIQ
HDIATRGMTD QRFEDEIVAK SAVLDALRMQ ETYWKDRARV KWLTDGDRST SFFHTYAKVR
AAKSQMSSIR VGERILTDPS DIAAHTVAFY QNLYDIPSPS TNVEEVCSVI PSLVTDDENV
VLSAIPTSEE IRSAVFSMDG SSAPGPDGFS GSFYQACWDI VGSDVVACVR QFFLQNWILP
NMNCNFLVLI PKVPNAQLIT QFRPIALANF LFKIIPKILA SRLGSIATRI ISPQQSAFLP
GRRINHCIGM VSECFNLLDR KAYGGNVGIK VDIAKAFDTL NWDFLLRVLS NFGFSPTFTS
WVSSILHSAR LSLLINGSPQ GFFTCSRGVR QGDPLSPLLF CLAEEALSRG LHLLLQTRQL
KPISFPRNCT APSHVLYADD LMVFCRGDKN SLKRLRGFFD RYSAASGQFI NAEKSTFYLG
ARSGHRTGTV QRILGFHAGR LPLIYLGVPI FCGKPRSCHL QVIADRAKSK LMGWQGRLLS
MAGRTQLVQS VFQSMLLHSF SVYQWPAYLV KKLSTWARNF IWSGNIETRK IVTVTWTQVC
APKKEGGVGI RDLATLNSAA VLRFAWNSFT SLNQWGDYMR TRYPILSSSK VRYRKSSIWP
GFRSIALHIT HNCRWIIGDG RSVSFWKDKW LQDPILDMLG FFDWSGFSDL RVADFISDHS
WQFPSFFLDT FPDLYRKISD ICLPLDTEPD MLIWETTASG ELSFTDSYNL LRRHFIVRDW
ASTIWHSFIP PRFSFLAWRI LLDRLPTDDR LKRGGIPIVS ICQLCNSSAE SALHLFLHCP
FSQHLWGWLA TQFGTSFPAY DSLLDFWVGF CQKGFSPQLY NLWLAAGLLT FMEIWKARNR
LRFDNRSPIF STLCCSIMAW IRQFGSLVPG YYKGVLDSRL LSSLGVCPKP RKAPKIQRVL
WHPPLPPWVK VNTDGLAKGN PGPAACGGVF RDASGVYLGS FCQPLGCNSS FYAELYAVIV
SIEVAFTRGW TTLWLESDSI SVLASLSSNS FSPPWDLRVR WQNCLKNIQQ MQFRRTHIFR
EGNAAADKMA NLGVSKHSFT WYPSPPAELH RYLQADFLGL PNYRFTGC
//
