ID A0A2P6RJV4_ROSCH Unreviewed; 519 AA.
AC A0A2P6RJV4;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=ceramide glucosyltransferase {ECO:0000256|ARBA:ARBA00012699};
DE EC=2.4.1.80 {ECO:0000256|ARBA:ARBA00012699};
GN ORFNames=RchiOBHm_Chr2g0091861 {ECO:0000313|EMBL:PRQ46703.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ46703.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ46703.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC {ECO:0000256|ARBA:ARBA00004760}.
CC -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ46703.1}.
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DR EMBL; PDCK01000040; PRQ46703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6RJV4; -.
DR STRING; 74649.A0A2P6RJV4; -.
DR EnsemblPlants; PRQ46703; PRQ46703; RchiOBHm_Chr2g0091861.
DR Gramene; PRQ46703; PRQ46703; RchiOBHm_Chr2g0091861.
DR OMA; SKVNWMM; -.
DR OrthoDB; 444471at2759; -.
DR UniPathway; UPA00222; -.
DR Proteomes; UP000238479; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008120; F:ceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102769; F:dihydroceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR025993; Ceramide_glucosylTrfase.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF13506; Glyco_transf_21; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:PRQ46703.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PRQ46703.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 519 AA; 58434 MW; 0385AAE5B92BAE2D CRC64;
MSTTLDPLDS LLFSLSRTLC TPLAVFIQLQ GCLICLILAL GWACAAYVRN REIRRMKDST
RRGNSFAFLC QDIMELEHSS QAKLPRVSVV MPLKGFGEHN LHNWRSQITS LYGGPLEFLF
VVESTEDPAY RAVSMLLSEL KDEVEAKIVV AGLSTTCSQK IHNQLVGVDK MHKDSKYVLF
LDDDVRLHPG SIGALTTEME KNPDIFIQTG YPLDLPSGSL GSYCIYEYHM PCSMGFATGG
RTFFLWGGCM MMHADDFRLD RYGVVSGLRD GGYSDDMTLA AIAGAHKRLI TSPPVAVFPH
PLASDLSFSR YWNYLRKQTF VLESYLTKVN WIMNRALFTV HCYLSWGFVT PYLMAMIHVT
AALRMYIKEY SVEETTFTFG GLTLVGCLAV CTIVELLSMW NLTRIEVHLC NMLSPEAPNL
SLATYNWGLV FIALLVDNFL YPISAFRSHF TQSINWSGIR YHLKNGKIFK IERSKDMGPI
YTDLGGKHLG KKGAPPKLSF LSSLARSLAQ WHQPKKYDS
//
