ID A0A2P6RKS2_ROSCH Unreviewed; 738 AA.
AC A0A2P6RKS2;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU364117};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU364117};
GN ORFNames=RchiOBHm_Chr2g0095381 {ECO:0000313|EMBL:PRQ47036.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ47036.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ47036.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU364117};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364117}.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446, ECO:0000256|RuleBase:RU364117}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ47036.1}.
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DR EMBL; PDCK01000040; PRQ47036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6RKS2; -.
DR STRING; 74649.A0A2P6RKS2; -.
DR EnsemblPlants; PRQ47036; PRQ47036; RchiOBHm_Chr2g0095381.
DR Gramene; PRQ47036; PRQ47036; RchiOBHm_Chr2g0095381.
DR OMA; RIVCHYN; -.
DR OrthoDB; 5474026at2759; -.
DR Proteomes; UP000238479; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF157; ATP-DEPENDENT DNA HELICASE Q-LIKE 3; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU364117};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU364117};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364117};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU364117}; Nucleus {ECO:0000256|RuleBase:RU364117};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479}.
FT DOMAIN 46..221
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 248..392
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 628..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 81928 MW; 588023BDDEEB1B68 CRC64;
MKKSPLPLQN ASGASKNQKL GKEALVKLLR WHFGHPEFRG KQLEAIEAVL SGRDCFCLMP
TGGGKSMCYQ IPALAKKTGI VLVVCPLIAL MENQVMALKE KGIAAEYLSS TQTTQVKKKI
HEDLDSGKPS LRLLYVTPEL IATPGFMTKL TKIHSRGLLN LIAIDEAHCI SSWGHDFRPS
YRKLSSLRSH LPGVPTLALT ATAVPKVQKD VIESLRLQNP LVLKSSFNRS NIYYEVRYKD
LLHNVYADLS DVLKSSGDIC AIVYCLERTM CDYLSVHLSQ NGISCAAYHA GLNDKLRSSV
LDDWISSKIQ VVVATVAFGM GIDRKDVRIV CHFNIPKSME GFYQESGRAG RDQLPSRSLL
YYGIEDCKRM KFILSNAENK KSKASNSQEE LSKKSLTDFQ QMVEYCEGSG CRRKKILENF
GEKVPVTLCS KTCDACKHPN LVAKYLEELA TACIVRQKAG SSRIFVGSSS NKVNEDQSSE
FWNRDDEASC SEEDISDSDD DVADLVAVKS LTRSKLIDEK LEALQRAEEK YYQNKSDKQT
DKLNKNAISD TLREASKQRL ENAVKQAQQR LGNLKIEVEK SASFLENECY KKYGKTGKSF
YYSQVASTVR WLSTVNSTDL TDRLCPITSS PSENTPLKTA PSASQSPLVE TGPFATLSPL
VDRATEITGN DLHESVRLEA SVALSPTQSD SPSTILPAIP SFSEFINSKK VTDNRSSASE
KQSPNGVEKN PEKKMRLR
//
