ID A0A2P6RNJ5_ROSCH Unreviewed; 909 AA.
AC A0A2P6RNJ5;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=[histone H3]-lysine(27) N-trimethyltransferase {ECO:0000256|ARBA:ARBA00012186};
DE EC=2.1.1.356 {ECO:0000256|ARBA:ARBA00012186};
GN ORFNames=RchiOBHm_Chr2g0105971 {ECO:0000313|EMBL:PRQ48013.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ48013.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ48013.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+)
CC + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:60292, Rhea:RHEA-COMP:15535, Rhea:RHEA-
CC COMP:15548, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:61961; EC=2.1.1.356;
CC Evidence={ECO:0000256|ARBA:ARBA00000090};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ48013.1}.
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DR EMBL; PDCK01000040; PRQ48013.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6RNJ5; -.
DR SMR; A0A2P6RNJ5; -.
DR STRING; 74649.A0A2P6RNJ5; -.
DR EnsemblPlants; PRQ48013; PRQ48013; RchiOBHm_Chr2g0105971.
DR Gramene; PRQ48013; PRQ48013; RchiOBHm_Chr2g0105971.
DR OMA; DESICRQ; -.
DR OrthoDB; 902834at2759; -.
DR Proteomes; UP000238479; Chromosome 2.
DR GO; GO:0031519; C:PcG protein complex; IEA:InterPro.
DR GO; GO:0140951; F:histone H3K27 trimethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003727; F:single-stranded RNA binding; IEA:EnsemblPlants.
DR GO; GO:1990110; P:callus formation; IEA:EnsemblPlants.
DR GO; GO:0009294; P:DNA-mediated transformation; IEA:EnsemblPlants.
DR GO; GO:0009965; P:leaf morphogenesis; IEA:EnsemblPlants.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IEA:EnsemblPlants.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:EnsemblPlants.
DR GO; GO:0009909; P:regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:1900055; P:regulation of leaf senescence; IEA:EnsemblPlants.
DR GO; GO:0009737; P:response to abscisic acid; IEA:EnsemblPlants.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IEA:EnsemblPlants.
DR GO; GO:0010048; P:vernalization response; IEA:EnsemblPlants.
DR CDD; cd10519; SET_EZH; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR026489; CXC_dom.
DR InterPro; IPR045318; EZH1/2-like.
DR InterPro; IPR025778; Hist-Lys_N-MeTrfase_plant.
DR InterPro; IPR041355; Pre-SET_CXC.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR PANTHER; PTHR45747; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR PANTHER; PTHR45747:SF4; HISTONE-LYSINE N-METHYLTRANSFERASE E(Z); 1.
DR Pfam; PF18264; preSET_CXC; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM01114; CXC; 1.
DR SMART; SM00717; SANT; 2.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51633; CXC; 1.
DR PROSITE; PS51576; SAM_MT43_EZ; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PRQ48013.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PRQ48013.1}.
FT DOMAIN 646..745
FT /note="CXC"
FT /evidence="ECO:0000259|PROSITE:PS51633"
FT DOMAIN 760..875
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 360..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..902
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 101972 MW; D8C6127E477D43AB CRC64;
MASKASPSAS ANRSEPHQDP PVTGTEENAL ALNLKEISLI IDSLQKQVIS NRGVSIKKRM
EENRQKLAGV TNNFYNLSME RRSSSLLYPG KSVDLLTKRQ QDAFKLQNGD ESNGSNDSSQ
EDGHGSTAVL LESNVAVKNA VRPIKLPEVK RLPPYTTWVF LDRNQRMTED QSVVGRRRIY
YDQNGGEALI CSDSEEEAID EEEEKREFVE SEDYILRMTI KEAGVSDPVL ESLAQYFSRS
PAEVKARYEA LIKEEESVGI SKNTDKEDLS KNDNSFLDKD LDAALDSFDN LFCRRCLVFD
CRLHGCSQDL VFPAEKQTPR SPPDDENVPC GPNCYRSVRK SEGIATISCP VNDDLEEKDI
KKSSGLSRKK GKSFQSESAS SNAKNISESS DSDNETRQDD TCSHDPISSK TKVAGKSGIP
KRNSKRVAER VLVCMQKRQK KTMASDSDSI VDGGLCASDM KLRSNSCKDN EDTSSSSQKN
LKSSSSGRSR RESPLKDSNK VVQGEVLDGS SNEMITDPPA TSSDDNLRKE EYVDENIYKQ
ECSDDKTWKT IETSLFEKGI EIFGKNSCLI ARNLLNGMKT CWEVFQYMNY SDSKISCQAG
DAANSLVEGY SKGNNEARRR SRFLRRKGRV RRLKYTWKSA AYHSIRKRIT EKKDQPCRQY
NPCTCQTACG KQCSCLLNGT CCEKYCGCPK SCKNRFRGCH CAKSQCRSRQ CPCFAADREC
DPDVCRNCWV SCGDGSLGVP NQRGDNYECR NMKLLLKQQQ RVLLGRSDVS GWGAFLKNSV
SKHEYLGEYT GELISHREAD KRGKIYDREN SSFLFNLNDQ FVLDAYRKGD KLKFANHSPD
PNCYAKVIMV AGDHRVGIFA KERIASGEEL FYDYRYEPDR APAWARKPEA SGSKRDDGAP
SSGRAKKLA
//
