ID A0A2P6RZF6_ROSCH Unreviewed; 694 AA.
AC A0A2P6RZF6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=RchiOBHm_Chr2g0148451 {ECO:0000313|EMBL:PRQ51802.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ51802.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ51802.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ51802.1}.
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DR EMBL; PDCK01000040; PRQ51802.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6RZF6; -.
DR STRING; 74649.A0A2P6RZF6; -.
DR EnsemblPlants; PRQ51802; PRQ51802; RchiOBHm_Chr2g0148451.
DR Gramene; PRQ51802; PRQ51802; RchiOBHm_Chr2g0148451.
DR OMA; CYITIAC; -.
DR Proteomes; UP000238479; Chromosome 2.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IEA:UniProt.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003, ECO:0000313|EMBL:PRQ51802.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 102..302
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 350..684
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 694 AA; 79275 MW; CE00E07B75873B65 CRC64;
MWKLRFGDEG ANNDPYLFST NNFHGRQTWE FDPAAGTPEE RAEVEEVRLS FYNNRHRVQA
CSDLLCRMQL LGEKKFKQKI PQVKVEDGED CTYEKATAAF RRAATFYSAL QSPHGHWPAE
NAGPMFYIPP LVISLYITGH LSKVFSAEHF KEMLRYIYCH QNEDGGWGLH IQAPSMMFCT
LLNYICMRLL GEGPDGGLNN ACARARKWIL DHGGATHSSS WGKTYMAILG VYEWEGCNPI
PPEFWIFPSL FPLHPAKMYC YCRLTYLPIS YLFGKRFVGP ITPLILQLRE EMYNEPYNEI
QWGKVRHLCA KPLMMLACWI EDPNGKPFKK HLARVIDYIW VAEDGITTQA WDASLSVQAL
LAGNHTDELG SVLQKAHEFL NKSQIRDNPS GDFLSRFRHI SKGGWTFSDR DHGWQVSDCT
AECLKCCLLL SMMPTQIVGE PVEYERLYDA VNVILSLQNP NGGVSAWQPT GAPQWLEWFN
PVEFLEDVVI EYEYVECTSS SIQALALFRK LYPGHRKKHI DDFITNAACY LEDMQTPDGS
WYGRWGICFI YGTWFAIRGL KAAGRTYKNC EAIRRGVEFI LKIQRNDGGW GESYTSCTNK
IYTPLQGDRS NLVQTAMGLM GLIHGGQAER DPTPIHRAAK LLINSQLENG DFPQQELMGV
FNVNAMLHYA AYRNIFPIWA LGEYCSLPSF WIDV
//
