ID A0A2P6SBU9_ROSCH Unreviewed; 656 AA.
AC A0A2P6SBU9;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=Putative cycloartenol synthase {ECO:0000313|EMBL:PRQ56158.1};
DE EC=5.4.99.8 {ECO:0000313|EMBL:PRQ56158.1};
GN ORFNames=RchiOBHm_Chr1g0332701 {ECO:0000313|EMBL:PRQ56158.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ56158.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ56158.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ56158.1}.
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DR EMBL; PDCK01000039; PRQ56158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6SBU9; -.
DR STRING; 74649.A0A2P6SBU9; -.
DR EnsemblPlants; PRQ56158; PRQ56158; RchiOBHm_Chr1g0332701.
DR Gramene; PRQ56158; PRQ56158; RchiOBHm_Chr1g0332701.
DR OMA; ISFMHIN; -.
DR Proteomes; UP000238479; Chromosome 1.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016871; F:cycloartenol synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11764:SF44; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:PRQ56158.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 410..641
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 656 AA; 74377 MW; DA6CDB1109B6D567 CRC64;
MHGRYLVYMN GTVTIHCLLN CGFYRTFSRW GGFVVGDGDH ELGVKGEGEV RDALVVALEG
RMWCHCRMVY LPMSYLYGKR FVGLINDLIF SLRTELYTLP YHLIDWDQAR NLCAKEDLYY
PHPILQDMLW GCLHKVGKPL LMRWPLSNLR QKALTTVMYH IHYEDENTQY ICVGSVNKVT
TSVGLVDQKL VRRTLVGELV LTQVSCLVSE FLSTGRELRC QGFTAFALVL NMICCWVEDQ
NSEAYKCHLS RIKDFLWVAE DGMKMQGSNG SQCWDVALAV QAILSTNLVN EYGSVLKKAH
YFIKNTQVRR DSYGNLRYWY RHISKGGWPF STADNGWSVS DCTAEGLKAA LLLSRMPCEI
VGEAIAADQL HDAVNVVLSL QVQLDLATSY SRIAEYLCNR KSNDMYFISL TQQNSNGGFA
SYELTRSYAW LEMINPAETF GDIMIDYQYV ECTSSAVEGL NAFMKLYPGH RKKEIEACIA
KAVQFIESIQ LPDGSWYGSW GVCYTYGTWF GIKGLMAGGK TYQTSDSIRR ACHFLLSKQL
DSGGWGESFL SCQNKVYTNL EGNKPHIVNT GWAMLALIEA GQGERDPIPL HRAAKVLINS
QMENGDFPQQ QIMGVFNKNC MASYSAYRNI FPIWALGEYR NRVLVPQMHQ SKKISA
//
