ID A0A2P6SDX7_ROSCH Unreviewed; 926 AA.
AC A0A2P6SDX7;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=RchiOBHm_Chr1g0342071 {ECO:0000313|EMBL:PRQ56873.1};
OS Rosa chinensis (China rose).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Rosoideae; Rosoideae incertae sedis;
OC Rosa.
OX NCBI_TaxID=74649 {ECO:0000313|EMBL:PRQ56873.1, ECO:0000313|Proteomes:UP000238479};
RN [1] {ECO:0000313|EMBL:PRQ56873.1, ECO:0000313|Proteomes:UP000238479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Old Blush {ECO:0000313|Proteomes:UP000238479};
RA Bendahmane M.;
RT "The Rosa genome provides new insights in the design of modern roses.";
RL Nat. Genet. 0:0-0(2018).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRQ56873.1}.
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DR EMBL; PDCK01000039; PRQ56873.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6SDX7; -.
DR EnsemblPlants; PRQ56873; PRQ56873; RchiOBHm_Chr1g0342071.
DR Gramene; PRQ56873; PRQ56873; RchiOBHm_Chr1g0342071.
DR OMA; VQTMTFM; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000238479; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF453; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF00497; SBP_bac_3; 2.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000238479};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..926
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015149919"
FT TRANSMEM 594..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..855
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 476..815
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 892..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..926
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 764..818
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 926 AA; 103149 MW; 41517D868342540A CRC64;
MNIGLLLLFL VFCQGSHASG LITNVTTRPD VLNIGSMFTF DSVIGKIAKL AITLAVEDVN
SNPNILNGTK LSLKMHNTKS SDFLGIVEAL QFMENDTVAI IGPQSSATAH VISHIANELQ
VPLLSFAATD PTLSPVQFPF FVRTTQSDLF QMTAVVDLVV HYQWRDVIAI YVDDDFGRNA
IASLGDKLAE KRCKISYKVP LTPTATKDEI RKALISVSTM ESRILILHIY TSWGLQVLEE
AQEQKMMDSG YVWIATDWFS TILDTDPSLP LVQTNNIQGV LTLRMYTPDS QLKTEFKSRW
SNLTRARRLL NNTSFGLNTY GLYAYDSVLL LAQAIESFFA IGWNISFSND TNLRELSGGK
LNLDALNIFN GGRQLLKSIL EVNTTGLTGP IKFDADGNLL NPAFEVINVI GRGTRTIGYW
SNSSGLNVLP PEKLQMKMQT NGSSAGTQKL YSVIWPGQTT EKPRGWVFPY NGRKLRIGVP
HGVSYPEFVG IKGTDFSGYC IEVFQAALNE LPYGVPYEYV PFGDGIKNPE SNDLLHRVQI
GEFDGVVGAI TITTNRTKMV DFTQPYIESG LVVVAPIRKM DSSAWAFLRP FTPMMWGVTG
VFFLVVGTVV WILERRTNED FRGPPKRQFV TIVWFSFSTL FFSQKEQTGS TLGRFVVIIW
LFVVLILNSS YTASLTSILT VEQLSSPVKG IESLVTGTEP IGYQRGTFAE AYLTDELNIH
HSRLVALDSA EDYEKALKKG PSAGGVAAVI DKRAYMELFL SSRCGYSIVG QEFTKMGWGF
AFARDSPLAI DMSTAILMLS ENGNLQKIHD KWLMKSACSV EGAKQAVDRL HLKSFWGLFL
LSGIACFLAL LLYVLHMVRQ YYRHADSDIE CSQSTRRVKS FVSFVNKREQ EVKSVKSSSK
RRRTDRKSSN KKVHRQECSS DGLDES
//
