ID A0A2P6TFT2_CHLSO Unreviewed; 2067 AA.
AC A0A2P6TFT2;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=TPR repeat-containing isoform A {ECO:0000313|EMBL:PRW32972.1};
GN ORFNames=C2E21_8128 {ECO:0000313|EMBL:PRW32972.1};
OS Chlorella sorokiniana (Freshwater green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=3076 {ECO:0000313|EMBL:PRW32972.1, ECO:0000313|Proteomes:UP000239899};
RN [1] {ECO:0000313|EMBL:PRW32972.1, ECO:0000313|Proteomes:UP000239899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX 1602 {ECO:0000313|Proteomes:UP000239899};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TTC30/dfy-1/fleer family.
CC {ECO:0000256|ARBA:ARBA00009522}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRW32972.1}.
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DR EMBL; LHPG02000018; PRW32972.1; -; Genomic_DNA.
DR STRING; 3076.A0A2P6TFT2; -.
DR OrthoDB; 5477075at2759; -.
DR Proteomes; UP000239899; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR033396; DUF5107.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR039941; TT30.
DR PANTHER; PTHR20931:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 30; 1.
DR PANTHER; PTHR20931; UNCHARACTERIZED; 1.
DR Pfam; PF17128; DUF5107; 1.
DR Pfam; PF06963; FPN1; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000239899};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 1711..1733
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1745..1767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1773..1797
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1865..1890
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1902..1921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1933..1957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2029..2052
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 350..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1200..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 390..417
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2067 AA; 218981 MW; C1983D4E83AC94D9 CRC64;
MQMVGFSPEL AYGLAACRYR AGDLSGAAAA LADVVQAGVQ LHPELGIGTQ TEGMEARSVG
NSAKLKSTAL VEAFNLRAAI ELAMGSPSGA AAALSDMPPR AEHELDSVTL HNQALVSLAL
AAAGTGGTGS SSSGSSGIAQ SGAEAFDKLV HLLEHPPFPP ELAGNLLSLC CRPDSVPGGG
GPGPAERAAV AGRLLAEHGP AVEAAVPGEL LPLYEACVAR ASSAEEAAAR LDALAGTHIE
GLRRRVKAVQ DARWAGDAAG AAAGLQAYEE ALDAYVPVLM SLVQLHWEAG AYGRAQEVLQ
QSAEFCSDHP AWRLNLAHAL VAQEGGRLGE AAELYESILR HFAGGAAAPS AATANAPGGS
PAMAAPDASD SSGGSLLDVP PSAVANLCVC HVISSQNEAA EELLRRLEDE TTAAEAGAAG
AAGAAAVPPH LSLANLAIGT LYCSKGNFEF GISRVVHALE PLGGCLDAPR WHAVLLCLLA
MLDQVAKNML VLKDALVADL LGAVDGGMGC GRAAARPAGA THPRRAPAMS VTVKRKRVVI
PTYAPCAADR HPQFIETRVY QGSSGKVYPL PFIDRISEEA RDQEWDAVWL ENEHVRVQLL
PQLGGRIHVL QDKHNGYDAI YRQHVIKPAL VGLAGPWISG GVEFNWPQHH RPSTFMPCDV
SIERESDGAV TVWCSEHEPM QRMKGMHGVR LRPGSALVEL RVRLYNRTPL TQTFLWWANA
GVHVHDQYQS FFPPDVHYVA DHAKRAMSEF PLCRGRYYGV DYGSATDGSN DLSWYKNIPV
PTSYMACNSE HDFFGGYDHG KQAGLVHVAN HHISPGKKQW TWGDHPFGHA WDRNLTDSDG
PYIELMAGVY TDNQPDFSWL EPGETKTFSQ YWYPIQAIGP AQHANLHGAL SLSVQGGEGA
VGVAVTAEHP QAVIILERRG SAAGAGADGV PSEVLLRETA ALGPAAPLVK RVALPPGCAA
HKLTLRVLSA AAEAGGRCLL ELSPAPPAAE GEQQVPDPAT EPPAPQDVQS VDELYLTGLH
LEQYRHPTRD PCLYWREGLA RDPGDARCNT ALGKWHLRRG ECAEAERHLR SAVARLTARN
PNPADGEAYY LLGLALKWQG GRDKEAYAAL YKATWNYAWR APAYYALAQM DAAHGDWEAA
AQHCRAALAT NADFLQARNL CAAVLRRAGK AAEADELVLG SRALDPLDWW SAHLAASGSG
SGAAEDGTAA AGGGGGNRAG GDEDGSAATG LGCGTQTALD VALDYADAGL YSEALDVLEP
HVASPQPGTA PLLHHYQAYF RHRLGQEKKV CEALAAGAAA PSDYVFPARL QELAILQFAV
DQSPDDARAR FYLGCWLYDR RRYAEAIALW RGAVELDGDG LPSAWRCLGI AAFNIEQDAA
AAAAAYDRAF ALAPTDSRLL YERDQLAKRC GTSPAQRLAA LEAHPDLVRH RDALAAEACA
LYCQEGRPEE ARRLLEGRRW QPWEGGEGEA LAQHVRCHLA LARTALAAGQ AEEAVQLCQA
AMESPANLGE AKHLLANDSD VRYALGCALA AAGRQEEADE QWRAAAEFEG DFQSMAVCPF
SEQTLFSALA LRKLGREEDA HALLERLLEH AQVLAESQAR VDYFATSLPA MLLFHDDLQE
RQETKALFLE AQARMEEPEH EQEARGLLAS PAGSRRAAFE SDVGPIDRSA HTAACRALQG
SHFLSTWGQR GWEFAVGLIM LELHPSSLVL VAWWGLLDGL VSVLCGAAVG AWVDSQPRLH
AASRMYLLQN SCVAASAAAA LGLLWSSVRS GPLFWAGLVV TMAAGSASTL GALGSALSVE
REWTKALCGS DSAALAHLNA AMKRIDLTCL IASPILVGLV MQHAGEQSMG VVAATLVLLG
WNLPTAAAAL ALALLYFTVL SFGTLMTAYL KSLGLPEAEL AVYRGLGALS GILATVTFPP
LHRWLGLVAT GSLSIWLQLA CLLAGVAPAL AAALGAAVGA APRTYALVWG LVLSRFGLWS
FDLAANQLIQ ETVEHSALGA VSGVQGSLQS FCQMLAYAAG VLVPATESFV WLMAGSCCVV
GAAAALYTAF ALRARCGQNM HVVLQPV
//
