ID A0A2P6TXL1_CHLSO Unreviewed; 1415 AA.
AC A0A2P6TXL1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Kinase {ECO:0000313|EMBL:PRW58809.1};
GN ORFNames=C2E21_2517 {ECO:0000313|EMBL:PRW58809.1};
OS Chlorella sorokiniana (Freshwater green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=3076 {ECO:0000313|EMBL:PRW58809.1, ECO:0000313|Proteomes:UP000239899};
RN [1] {ECO:0000313|EMBL:PRW58809.1, ECO:0000313|Proteomes:UP000239899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX 1602 {ECO:0000313|Proteomes:UP000239899};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRW58809.1}.
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DR EMBL; LHPG02000004; PRW58809.1; -; Genomic_DNA.
DR STRING; 3076.A0A2P6TXL1; -.
DR OrthoDB; 6392at2759; -.
DR Proteomes; UP000239899; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR23257:SF962; KINASE SUPERFAMILY WITH OCTICOSAPEPTIDE_PHOX_BEM1P DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PRW58809.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000239899};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 896..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1188..1206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1042..1355
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 190..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1009
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1357..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1008
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 1069
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1415 AA; 149948 MW; 8CD0659A68467A44 CRC64;
MDASLQATES GHRPLRVLFC GHDMHYGYLF TSEALEGEEG VEVLQCERSE LPLLIRSADV
AVPLMSRLDA QLLRSAERLK LIIQYGVGVE GIDMQAASEL GIWVSNIPSA GTGNAVSCAE
HAIYLMMAVL RSHNEMADSI RHRRLGVPLG QTLFGKTVLI VGFGNIAKEL AVRLKPFGVR
ITALRRKPWS NSSAADCVEQ QPASGQPQGQ QLDEGMQVDA EQAEEQGMEE DGQQRTDQQA
AQQAGQQEGQ QAQPEGQRPG PQQPQQQVAQ QAAAQDVQQP AVRLHQAHDP ELDAAAEAAL
ADKGCWPADC ARLAGEADII ALTCHQDESN RSMVNAEFLA HCKQGVCIVN VARGGLMDYD
ALSEALFTGQ VAGLGLDVHP QEPLEPDHWL VHHPCVYLTP HIAGVTEISY RNMARIVADA
VLALKHGQPP ARLLNAPERP RGAEAAAAGT DDIYIRPQDV RPFEPWLPIN GGNRTVLLLG
ARGGGSGNAR GDGGSGSGGD GSLGPPVTLD FGGAVNLMYH PVHHQFITYN LALQGMAPAS
SGYAAGLTSQ MVGGAFWPST TGEPHHLMAF FNSTIRLVSA TCGRNSTAFS VAALHQVLGR
NDTVTQLDDQ TFFVGQRLNG SYTLRVLPTG DAAGNVRWSW DSTTVTCVRP QQPGGSVPSV
HQQTVPTGIA ANADELLHLL DSPAITTILL GGHISLQGAN LSTFQLPIVL QGRQVDIQSN
DELPKVLDLG GQPQLVYLSA TSSLTFQRVH VQGAAPPSQV MTSPARTTLI VSPSLWPTID
GEAGHQLIFE DASLQTVATP CSRNNTQIQV DLLCKMLGDD AVQHTSDTSY AIAPRFQQPT
PIRSILTREQ LGSTPYTFER SEISCIEDAG VGLAAELQAQ HALPPNSSSS GGLPGWVPAV
IAVPVGLLLA AAAMAGVILQ RRRRRRRAAT RLVPAKATTV AAEEERAPLT PRTGKMDRME
SGELKGKLPF DSVAGSDVVA ASPAGTAGPA SPMLSRTSST NHGSGSRLND GSLLPAAACP
APHQTTAVKL WRARFTGVIE GLEIGELLGR GAYGRVYKGR WNGAIVAAKV VEHSVAAGAS
EAGSMSREPL LCMSVSHPNC ITTYKLSAIR LLRGEGLMEP EDSASSVPLP HLPPLLLSGT
EGVEVADPYG PLEAGLYETW MVLEYCDRGS LADALAERRL VGKDGRTHMV AVLLCLLDVA
SGMSYLHSLG IVHGDLKPAN VLLKGVRNSV RGFQCKLGDF GLSRMLDGRS TYIQTGSLGT
PTHAAPELLR EGRLAVPADV YAFGVLAWEL VAGEEAWRGQ HPMQIILAVT QQGARPPPLL
DCPPPLAALM AACWQEDPQR RPTFADLLPQ LQGMLQAARK AGPPQPLPSR VASARSSAEV
PRPEGSPAPS PNVSASALPP AADAAAAVAP AQDGS
//
