ID   A0A2P6U099_CHLSO        Unreviewed;       526 AA.
AC   A0A2P6U099;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=peptidylprolyl isomerase {ECO:0000256|ARBA:ARBA00013194};
DE            EC=5.2.1.8 {ECO:0000256|ARBA:ARBA00013194};
GN   ORFNames=C2E21_1467 {ECO:0000313|EMBL:PRW59726.1};
OS   Chlorella sorokiniana (Freshwater green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX   NCBI_TaxID=3076 {ECO:0000313|EMBL:PRW59726.1, ECO:0000313|Proteomes:UP000239899};
RN   [1] {ECO:0000313|EMBL:PRW59726.1, ECO:0000313|Proteomes:UP000239899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UTEX 1602 {ECO:0000313|Proteomes:UP000239899};
RX   PubMed=29178410; DOI=10.1111/tpj.13789;
RA   Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA   Barney B.M.;
RT   "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT   conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL   Plant J. 93:566-586(2018).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
CC         Evidence={ECO:0000256|ARBA:ARBA00000971};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the SYF2 family.
CC       {ECO:0000256|ARBA:ARBA00010028}.
CC   -!- SIMILARITY: Belongs to the cyclophilin-type PPIase family.
CC       {ECO:0000256|ARBA:ARBA00007365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRW59726.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LHPG02000003; PRW59726.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P6U099; -.
DR   STRING; 3076.A0A2P6U099; -.
DR   OrthoDB; 315265at2759; -.
DR   Proteomes; UP000239899; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd01926; cyclophilin_ABH_like; 1.
DR   Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR   InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR   InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR   InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR   InterPro; IPR013260; mRNA_splic_SYF2.
DR   PANTHER; PTHR11071; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR   PANTHER; PTHR11071:SF561; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H; 1.
DR   Pfam; PF00160; Pro_isomerase; 1.
DR   Pfam; PF08231; SYF2; 1.
DR   PRINTS; PR00153; CSAPPISMRASE.
DR   SUPFAM; SSF50891; Cyclophilin-like; 1.
DR   PROSITE; PS00170; CSA_PPIASE_1; 1.
DR   PROSITE; PS50072; CSA_PPIASE_2; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:PRW59726.1};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239899};
KW   Rotamase {ECO:0000256|ARBA:ARBA00023110}.
FT   DOMAIN          11..174
FT                   /note="PPIase cyclophilin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50072"
FT   REGION          236..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        316..339
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  57280 MW;  4835D1D6291014CC CRC64;
     MASDLDNPRV FFDISIAGEE AGRIVMTLFA DVVPRTAENF RCLCTGEAGV ARGGKPLHYK
     GSLFHRVIPQ FMCQGGDFEN ADGTGGQSIY GDTFADENFD LKHTDGGLLS MANAGPGTNG
     SQFFITTAPC PWLDGKHVVF GKVTEGLPVV KRMESLGSKS GRTAQKIYIA DCGELPSKRQ
     IMAKILRERE EAAAMKQDPS FVDPDEEARA RLRALTAGGA KPALPFKTAQ DELRELEERE
     RQEELARQAA AGGAPALAVA AASDEDGEER RQDGAAAAGG GEQKGGDGEE GGAAYSVDPT
     AGMNARQKKL WELQQRMKAA RKANEHAVVA EKKKAAAAKA AESGPEGGGG AGGNKRKWFE
     DKQKKKEEEL ARLGLAPDKA YLLETAETAE ALAKKKEKKP APEGWEQFNQ ASLAAAYERR
     TEKIKPDRAE YEAAKASDPE FYRAADSLLY GQGKPSEAAV DRMVAELNDR RNKSFSRRRA
     HREDKDIDYI NDRNAHFNRK IERIFGEHTA EIKANLERGT ALPDHR
//