ID A0A2P6U0L1_CHLSO Unreviewed; 2284 AA.
AC A0A2P6U0L1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE SubName: Full=Transcription elongation factor SPT5-like protein 1 {ECO:0000313|EMBL:PRW59844.1};
GN ORFNames=C2E21_1680 {ECO:0000313|EMBL:PRW59844.1};
OS Chlorella sorokiniana (Freshwater green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=3076 {ECO:0000313|EMBL:PRW59844.1, ECO:0000313|Proteomes:UP000239899};
RN [1] {ECO:0000313|EMBL:PRW59844.1, ECO:0000313|Proteomes:UP000239899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX 1602 {ECO:0000313|Proteomes:UP000239899};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SPT5 family.
CC {ECO:0000256|ARBA:ARBA00006956}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRW59844.1}.
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DR EMBL; LHPG02000003; PRW59844.1; -; Genomic_DNA.
DR STRING; 3076.A0A2P6U0L1; -.
DR OrthoDB; 24955at2759; -.
DR Proteomes; UP000239899; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0140673; P:transcription elongation-coupled chromatin remodeling; IEA:InterPro.
DR CDD; cd06081; KOW_Spt5_1; 1.
DR CDD; cd06083; KOW_Spt5_3; 1.
DR CDD; cd06084; KOW_Spt5_4; 1.
DR CDD; cd06085; KOW_Spt5_5; 1.
DR CDD; cd09888; NGN_Euk; 1.
DR Gene3D; 2.30.30.30; -; 3.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041973; KOW_Spt5_1.
DR InterPro; IPR041976; KOW_Spt5_3.
DR InterPro; IPR041977; KOW_Spt5_4.
DR InterPro; IPR041978; KOW_Spt5_5.
DR InterPro; IPR005100; NGN-domain.
DR InterPro; IPR006645; NGN-like_dom.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR039385; NGN_Euk.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR039659; SPT5.
DR InterPro; IPR022581; Spt5_N.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR11125; SUPPRESSOR OF TY 5; 1.
DR PANTHER; PTHR11125:SF7; TRANSCRIPTION ELONGATION FACTOR SPT5; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF13906; AA_permease_C; 1.
DR Pfam; PF03439; Spt5-NGN; 1.
DR Pfam; PF11942; Spt5_N; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00739; KOW; 6.
DR SMART; SM00738; NGN; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:PRW59844.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:PRW59844.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000239899};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1710..1731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1738..1758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1770..1788
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1800..1820
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1826..1845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1852..1875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1895..1914
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1926..1952
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1972..1995
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2053..2070
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2082..2102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2108..2126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1212..1414
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2190..2213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..32
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..106
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2190..2204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2284 AA; 242407 MW; 71E873489988BCC0 CRC64;
MGRGGAGSEE HDEEEWNEEE EDVSDEASDE DEEEDVGRHR KKAEKAKPAK PAKKKKRSGF
IDDAAEEDDE DARPGRKRLR ASAFIDDIAE VDEDEDEDDD EDEGLDDLIA DEGDELPSAA
DLHKMRREIR EAELAAARDN EPNPEELEKY IKERFGNRSY ASYGYDEEGG DGRPRAVGQQ
ALMPTATDPK LWVVRCGEGQ EREAVVCLLQ KCYDLAKRGT PLLIKAAFCQ DHLKGYFYVE
AHKEAHVKEA LKGLRMIFQS KPPKLVPLKE MVDAIRVAKG AEKAIEAGSW VRMKGGIYKH
DLAKVIEADP SNQRATIKLV PRIDLAALAA RKPEDARANF GKQPKVKPPA KPFNPDEAKA
HRLDVHQQRD RATGDVFYIL NNNQRFLEGY LVRSIAMKSL ILQESLPPLD ELQKFNAAAQ
SEDAGPTDLA GIMQNLQTEG GAGEGSAAPA PKFEKLDRVL VVEGDLKNIK GVVQHIAEDG
GIMVQPQDES LGDFKDVIRF EPRELSKYFE SGEHVKVVHG QHEGETGMVV RVETPVAYVF
TDSSHQEIKV FVRDLTLAVA TASSADSLGG YEMHDLVVLD NTTVGVIVNV EQDALRVLTN
QGRPDKPDIR VCRLPDIKRK MNNRRASVKD GAGNDVNVND AVDVVDGPLK GRSGTVKYIM
RGFLFIQTRE VSENAGFICL QARHTKVRGG RSAARGGGVG MTPGRSPAYG LLASPHPSRG
PQQPVLASPG RQGGFGGGPG GPPGSGVYSG RITTQQDKML EGRSITIRKG PFRGMRGRVI
SATATHVRLE LEAQMKTVTV DRSHLAMEEG GRAEAAPRPG FAYPAANTPM AAAGRTPMHP
GVTATPMHYS SMGQATPMHP GMTPGRETLT KTPAYDPAWA ATPAHPGFGG GGPAGPGGYP
NAGTPAFADT PGTVNPGGYG GAAYAPSPAA YAPSPAGYAP SPAGYGPAGT PAVAGTPGMY
APAGTPGMYA PAGTPGMYAP AGTPGVYGAA DMPAPTPGGG QYGGPATAGS SQDYSHWVDV
EVKLPGGDHA VVRSVEGGTA TVTVGQEAGE GRYAYPPDAA SRAVPCSDMQ LVCPDRKEAI
RIVRGDLAGQ YGDLVGTDGG DGIIKLGADI KIMPLADIGR LAVQPEAGGD TFDTTSNTTQ
PCTELFCPLY SLGIAPDPLR QAATARRRSL LQNENTSAGS GAAKGTALPE VYSAVGLDSG
ILASEFKRKR LNLALLLDVS GSMDSPFNRY YYDSITGEPK NLTDREANMT KVDVAKEVLT
GIVDLLKPED SFSITLFSDG ACTPKAFGPV SCVDIPTLKA QIMKDVNATS GTALSTGWDQ
ATAELKPHAS GNLSEVENRI ILISDQEPNS GDFTTEGLAA RLKNNSEAGI FTTIIGVGLD
FNTELVEAIS KVKGANYFSV HSPGEFKQRL VDEFDYAVTP LVFDLALQVV TTGAGNASDD
SGWRILHVYG SPNPNETALS SDGTVMRVHT LFPSPKTEQG IKGGVVLLRL RPPAKGANTP
LRLAVTYSDR EGKQFRSERT VALPAGFTAA AAASSGEAPM SYYQSTGVRK AVLLARYTDM
LQGWLIDEWN AIDANDTAVI NATLCGTFPS AFCPDVDAIA KYEVSPAPEG ACKVNRWLLP
DGCLLPVPFP VMVQLSEWER TSHNLTVSPD AKQAFQAFLP YLQEEMVAVN DTSLQQEVDL
LNTLIAVTVE QHLLRSGTND LPKTLSLADL VFLGIGSIIG AGVFVLSGVA ANELAGPAVI
VSYLVAATAA LLSALCYAEM AVSLPVAGGA FNYISVSFGE LAAWTVAWNI SLETTLSSAA
VARGFASYLA TLIGLSASAL RISVGPIQLD PAAALLVLLL TALLIKGTKE SSLFNMVVSG
LNVASILFVL CAGFPSAKAS NLSPFAPFGG KGVFAASAVV FFAFVGFDYV ANAAEEATDP
AKDLPWGIVG SLGVATLLYV LMSLCIVMMV PYQNIDVNAP FSAAFLDHGM AWAAKIVSLG
AVLGIVTSSM TGLLGQSRLF VVLGRERLLP ARLAAVSPRT GTPVEATLLT GCMAATLALL
LDIGLLAELV SIGTLYVFIC VCSGTLYNRY HQPGSGSSAK PVLAALLAMI SMAAAFSLSF
TFDAGWPAVL VFLLLFGLAA ASLYLLPVQH VPEKFRVPLF PATPSLGILF TVHLIGSLGW
LAYVRFGVWM AIGLALYALY GVHGAEQRER EHDSELEEAR ARESNGAEAP LPHQLTSLDH
EGLMGGIELS SAPQPGYQLE IEQQQDEPPA VLSALARLAG RYGGSDRARL MAGRLDSSYD
PGED
//
