ID A0A2P6U1I6_CHLSO Unreviewed; 745 AA.
AC A0A2P6U1I6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=General transcription and DNA repair factor IIH helicase subunit XPD {ECO:0000256|ARBA:ARBA00014344};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=C2E21_1398 {ECO:0000313|EMBL:PRW60183.1};
OS Chlorella sorokiniana (Freshwater green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=3076 {ECO:0000313|EMBL:PRW60183.1, ECO:0000313|Proteomes:UP000239899};
RN [1] {ECO:0000313|EMBL:PRW60183.1, ECO:0000313|Proteomes:UP000239899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX 1602 {ECO:0000313|Proteomes:UP000239899};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the helicase family. RAD3/XPD subfamily.
CC {ECO:0000256|ARBA:ARBA00009146}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRW60183.1}.
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DR EMBL; LHPG02000003; PRW60183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6U1I6; -.
DR STRING; 3076.A0A2P6U1I6; -.
DR OrthoDB; 124793at2759; -.
DR Proteomes; UP000239899; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR010643; HBB.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR InterPro; IPR001945; RAD3/XPD.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF1; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF06777; HBB; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR PRINTS; PR00852; XRODRMPGMNTD.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:PRW60183.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000239899}.
FT DOMAIN 1..264
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT COILED 228..255
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 745 AA; 84120 MW; 1C8778D343D7EB9D CRC64;
MLELKHALDA KGHCLLEMPT GTGKTITLLS LITSYQLAHP EVGKLIYCTR TVPEMEKVLA
ELKELMDYRA RYFTDAPGGA PKILALGLSS RKNLCIHPWV SEEGSRESVD AKCMKLTAPW
VRERAGQDED IETCGFYEGL EGAGPDGRLD AGVYTLHDLR VLGRKQQWCP YFLARRMVAY
ANVVVWNYQY MIDPKVSQMV SREMERECVV VFDEAHNIDN VCIEALSVNL RQQTLDAASR
NIQTLKREIE RTKQTDAGRL RAEYQRLVQG LQAQGVLQQG GAGEADGTQQ WLANPALPDD
ILREAVPGNI RRAEHFIAFL QRFVQHLRSR LAVNEVVSVT PTAFLEKLQE EVAIEGKTLR
FCYDRLVSLM KTLEITASDD FHGVHMVADF ATLVGTYSRG FAIIIEPFDD RLPSVPDPVI
QLSCLDASLA MRPVFSKYQS VVITSGTLSP IDLYPRILNF QPVCVASLNM TLTRECLCPV
VLTRGGDQLP VSTKFDMRSD PQVIRNYGRM LVDLAATVPD GIVCFFVSYL YMDTIVSRWN
DMGILQELMQ HKLVFIETQD VVETTLALDN FRRACDCGRG AVFFSVARGK VAEGIDFDRH
YGRCVVMFGV PYQYTLSRIL RARLEYLRET FQIKENDYLA FDAVRQAAQC VGRVIRSKAD
YGLMVFADKR YQRHDKRDKL PSWITQHLKD AHLNLSTDML LCIAREFMRS MAQPYDRAAV
GRSLLSEATV NALDSARPPA DPMET
//
