ID A0A2P6VCQ6_9CHLO Unreviewed; 1157 AA.
AC A0A2P6VCQ6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=NADH:ubiquinone oxidoreductase 76 kDa subunit {ECO:0000313|EMBL:PSC71880.1};
GN ORFNames=C2E20_4814 {ECO:0000313|EMBL:PSC71880.1};
OS Micractinium conductrix.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Micractinium.
OX NCBI_TaxID=554055 {ECO:0000313|EMBL:PSC71880.1, ECO:0000313|Proteomes:UP000239649};
RN [1] {ECO:0000313|EMBL:PSC71880.1, ECO:0000313|Proteomes:UP000239649}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 241.80 {ECO:0000313|EMBL:PSC71880.1,
RC ECO:0000313|Proteomes:UP000239649};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404, ECO:0000256|RuleBase:RU004523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSC71880.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LHPF02000012; PSC71880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6VCQ6; -.
DR STRING; 554055.A0A2P6VCQ6; -.
DR Proteomes; UP000239649; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd02773; MopB_Res-Cmplx1_Nad11; 1.
DR CDD; cd00464; SK; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.200.210; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00109; Shikimate_kinase; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR010228; NADH_UbQ_OxRdtase_Gsu.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR InterPro; IPR015405; NDUFS1-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR000623; Shikimate_kinase/TSH1.
DR NCBIfam; TIGR01973; NuoG; 1.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR Pfam; PF09326; NADH_dhqG_C; 1.
DR Pfam; PF01202; SKI; 1.
DR PRINTS; PR01100; SHIKIMTKNASE.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00641; COMPLEX1_75K_1; 1.
DR PROSITE; PS00642; COMPLEX1_75K_2; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000239649};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Ubiquinone {ECO:0000313|EMBL:PSC71880.1}.
FT DOMAIN 362..440
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 440..479
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 577..633
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1029..1157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1070..1088
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1157 AA; 123792 MW; FB23BDC2DB3DEC67 CRC64;
MQVSLMAAAA RATVPQPTSR RPQQHAALRA LPVRQHAVAV AATRLQAAAR RQRRFVAVAA
AAGTPRDFEE KKERFAAANK DYAVLTQQIE DTSKEVVEEL QGTSLFLVGM MGSGKSTVGK
LVSKALGYCF FDTDTLIEQL AQKKVSEIFA EEGEAAFREL ETQVLAELAP FKNCVVATGG
GVPMRAENWG HMQGGISIWL NGPPTLLAHR VVGDGTATRP LLSQDGGSEG GGGAAGGDAY
AAAVARLSAL LEERQQLYQI SDLTVSLEGS GPDADLGAPA MMVCYRVLVL LNQRIKADTE
ERKRRMDFEI VQDELPSTMR VMESRAARYR ALERLRQLGQ PGSSLWARGM AAAAQPAPVD
DGMIELTVDG QPVRVPKGSN LLQACDAAGK DIPRFCYHQR LSIAGNCRMC LVEVEKSPKP
VASCAMPAGP GMNVKTDTPL VKKAREGVME FLLINHPLDC PICDQGGECD LQDQSMVFGS
DRSRFTEVKR AVADKNLGPL VKTVMTRCIH CTRCIRFAKE IAGTDDLGIT GRGRDAEVGT
YVEKLMTSEL SGNVIDLCPV GALTSKPSAF TYRNWELKST ESVDTSDALG ANIRVDARGV
EVIRIVPRLN EEVNQEWISD KARFQYDALR YQRLNVPYVR GEKGLQQANW PQAFAAIRAA
ASKVQGHEMR AVAGRLADAE SMVALKDLMN RLGCGDLRSE AGFADLDADT RSAYLFNSTV
AGIDQADAVL LVGCNARLEA PVLNARLRAA NLAGVPVAYV GAPADLTYPV EVLGEGADAL
DKLTKAGSEF LKRFKGAQRP MVIVGAGVLQ RADRDAVMQK VANVVDKAEV VREGWNGFNV
LHDAAARVAA LDVGFLPSAR ARASKAAPKL VYLLGADDYS DADVPAGAFV IYQGHHGDRG
AARADVVLPS TAYTEKYATY VNTEGRPQTT KTAVASLGDA RDDWKVVRAL SEVLGAPLPY
NTIDDVRRRL SDVAPHLARR DAVEAPLWLA GEYWKAVGNS KAAAVPGSLA SGIANFYQTD
AISRASKVMA NEPAAGQPAR QHPRALRPPG AELRRGLPRE AEGSGNGSDQ FDEEEASAGS
TSASDGAEQV LTEALADEGE AQKEEQSMWG DEDEGAESDA SGMADIPDSS EAEAGDAAGS
AGDWEEEAGA DDEDNGW
//
