ID A0A2P6VKN6_9CHLO Unreviewed; 501 AA.
AC A0A2P6VKN6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=beta-ketoacyl-[acyl-carrier-protein] synthase III {ECO:0000256|ARBA:ARBA00012333};
DE EC=2.3.1.180 {ECO:0000256|ARBA:ARBA00012333};
GN ORFNames=C2E20_2193 {ECO:0000313|EMBL:PSC74644.1};
OS Micractinium conductrix.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Micractinium.
OX NCBI_TaxID=554055 {ECO:0000313|EMBL:PSC74644.1, ECO:0000313|Proteomes:UP000239649};
RN [1] {ECO:0000313|EMBL:PSC74644.1, ECO:0000313|Proteomes:UP000239649}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 241.80 {ECO:0000313|EMBL:PSC74644.1,
RC ECO:0000313|Proteomes:UP000239649};
RX PubMed=29178410; DOI=10.1111/tpj.13789;
RA Arriola M.B., Velmurugan N., Zhang Y., Plunkett M.H., Hondzo H.,
RA Barney B.M.;
RT "Genome sequences of Chlorella sorokiniana UTEX 1602 and Micractinium
RT conductrix SAG 241.80: implications to maltose excretion by a green alga.";
RL Plant J. 93:566-586(2018).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSC74644.1}.
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DR EMBL; LHPF02000004; PSC74644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P6VKN6; -.
DR STRING; 554055.A0A2P6VKN6; -.
DR Proteomes; UP000239649; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00830; KAS_III; 1.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR HAMAP; MF_01815; FabH; 1.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR004655; FabH.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR023313; UBQ-conjugating_AS.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR NCBIfam; TIGR00747; fabH; 1.
DR PANTHER; PTHR43091; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE; 1.
DR PANTHER; PTHR43091:SF1; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III, CHLOROPLASTIC; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00183; UBC_1; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000239649};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 4..151
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT ACT_SITE 89
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10133"
SQ SEQUENCE 501 AA; 53039 MW; 9F235B1AC79E6C4C CRC64;
MTTSAQLRLL SDLKAIEVEP PEGCSASPLS EDNLFVWGAS ILGPVETPWE GGIFQLRVTF
SEHYPDKPPR VRFVSECFHP NVYSDGTLCL DIIQDSWSPC HNICSILTSI QSLLTDPNCA
SPANPEAAQL YTTNRKEFNR KVRRIAQKSV EIPAARRLRR AAVVAAAAGG GGGSGIKLAG
VGSSVPEKFL TNDDLAQLVD TSDEWIISRT GIKKRHILSE GESLGSHAAA ASRRALEMAG
VAAEEVELVI MATSSPDDLF GSATTVQAAI GATGAAAFDL TAACSGFVMG LVTGAQYIKA
GTYKTVLVIG ADALSRYIDW RDRGTCILFG DGCGAVVLRA QEGSCGLLGI DMHSDGNGMR
HLNCAFAGEP MKPLSSGDAS KQGAYNNLHM NGQEVFKFAV RAVPTVIEAA LADAGMEKQQ
IDWLVMHQAN MRIMSSAADR LGVPPERVVS NLSQYGNTSA ASIPLALDEA VRRGDIKPGE
VLAMAGFGAG LSWASAIVRW G
//
