ID A0A2P7MWS3_9CYAN Unreviewed; 712 AA.
AC A0A2P7MWS3;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Nitrate reductase catalytic subunit {ECO:0000313|EMBL:PSJ05680.1};
GN ORFNames=C7K55_06470 {ECO:0000313|EMBL:PSJ05680.1};
OS Cyanobium usitatum str. Tous.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Cyanobium.
OX NCBI_TaxID=2116684 {ECO:0000313|EMBL:PSJ05680.1, ECO:0000313|Proteomes:UP000243002};
RN [1] {ECO:0000313|EMBL:PSJ05680.1, ECO:0000313|Proteomes:UP000243002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tous {ECO:0000313|EMBL:PSJ05680.1,
RC ECO:0000313|Proteomes:UP000243002};
RX PubMed=30117250; DOI=.1111/1462-2920.14377;
RA Cabello-Yeves P.J., Picazo A., Camacho A., Callieri C., Rosselli R.,
RA Roda-Garcia J.J., Coutinho F.H., Rodriguez-Valera F.;
RT "Ecological and genomic features of two widespread freshwater
RT picocyanobacteria.";
RL Environ. Microbiol. 20:3757-3771(2018).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSJ05680.1}.
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DR EMBL; PXXO01000006; PSJ05680.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7MWS3; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000243002; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000243002}.
FT DOMAIN 11..69
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 712 AA; 75513 MW; 0B74C606D27D6C64 CRC64;
MASDPASPAA SPAALAQCPY CGVGCGLELK PPDESGGAWI ARGDRHHPSS LGQVCIKGAT
VGETLHPNRL TTPLWRARID QPLEPISWQR AFTILVERIQ ATLATKGPQA LAIYGSGQFL
CEDYYAANKL LKGALGSNNF DANSRLCMSS AVAGYARSLG SDGPPCCYDD LDLADLVLLI
GTNTAECHPV LFQRLLKRRR KGNGLRLVVV DPRATATSDA ADLHLAIAPG SDLALLCGLG
HLLLEHGGVD QACVAAHTEG FAELEILWRA WQPARAAAVC GIAEADLRQL AEWWCQATGA
LSLWSMGVNQ SREGSATVAG ICNLHLVSGQ IGRPGAGPFS LTGQPNAMGG REVGGLAQLL
PGYRAVGDPA HRAEVESHWG FAAGSISPEP GLAVWQQIEA MERGELDLWW VAGTNPLVSL
PSLDRVRAAV ANCPLVVLSE AYAGTETEAL AHLVLPAAQW SEKTGVMVNS ERRVTLCSAF
RQPPGEARAD WAIFAELGRR LGFVDQFSYA SAAEVYAEFV ALTAGRLCDS SGLSHRLLAE
HGPQQWPFPA GTAPGVGAAR LYVDLAFPTP SGKARLWADP PLGLAEPPCD SYPLVLTVGR
VLGHWHTMTR TAHVARALKA HPEPLLEVHP SDAAHAGLVD GARAQVWSRR GAVSVKVQIT
DRIRPGTVFL PMHWGASQGE LACEANRLMH ELGCPISMQP ELKAAAVALT PA
//
