ID A0A2P7MYN6_9CYAN Unreviewed; 304 AA.
AC A0A2P7MYN6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=TlyA family rRNA (Cytidine-2'-O)-methyltransferase {ECO:0000313|EMBL:PSJ06312.1};
GN ORFNames=C7K55_05155 {ECO:0000313|EMBL:PSJ06312.1};
OS Cyanobium usitatum str. Tous.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Cyanobium.
OX NCBI_TaxID=2116684 {ECO:0000313|EMBL:PSJ06312.1, ECO:0000313|Proteomes:UP000243002};
RN [1] {ECO:0000313|EMBL:PSJ06312.1, ECO:0000313|Proteomes:UP000243002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tous {ECO:0000313|EMBL:PSJ06312.1,
RC ECO:0000313|Proteomes:UP000243002};
RX PubMed=30117250; DOI=.1111/1462-2920.14377;
RA Cabello-Yeves P.J., Picazo A., Camacho A., Callieri C., Rosselli R.,
RA Roda-Garcia J.J., Coutinho F.H., Rodriguez-Valera F.;
RT "Ecological and genomic features of two widespread freshwater
RT picocyanobacteria.";
RL Environ. Microbiol. 20:3757-3771(2018).
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSJ06312.1}.
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DR EMBL; PXXO01000004; PSJ06312.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7MYN6; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000243002; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:PSJ06312.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000243002};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transferase {ECO:0000313|EMBL:PSJ06312.1}.
FT DOMAIN 5..69
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 304 AA; 32573 MW; 4583075F3045298C CRC64;
MARKQRLDLE LVARGLAASR QQAQLLIRAG RVRHGDKVLD KPGTEVLPEA ELLVQQLPRY
VSRGGEKLVR ALEAFPIAVQ GRVCLDGGIS TGGFSDCLLQ HGACRIYGID VGYGQTAWSL
RSDPRVVLKE RTNLRHLTPD ALYGPEDPWP DLAVADVSFI ALALVLPALL ALLQPQAPVD
LLLLVKPQFE VGKGRVGKGG VVRDPVAHCD AIEGVITAAS GLGLVACGLV ASPITGPAGN
HEYLLWLRRS DCDGQVGMGD VAEDVFEPVE QLVESAQSDP KFRPAPISPE QIKTLVASTL
TPRE
//
