ID A0A2P7MZK5_9CYAN Unreviewed; 234 AA.
AC A0A2P7MZK5;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=2-phytyl-1,4-naphtoquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_01982};
DE EC=2.1.1.329 {ECO:0000256|HAMAP-Rule:MF_01982};
DE AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_01982};
GN Name=menG {ECO:0000256|HAMAP-Rule:MF_01982};
GN ORFNames=C7K55_04225 {ECO:0000313|EMBL:PSJ06656.1};
OS Cyanobium usitatum str. Tous.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Cyanobium.
OX NCBI_TaxID=2116684 {ECO:0000313|EMBL:PSJ06656.1, ECO:0000313|Proteomes:UP000243002};
RN [1] {ECO:0000313|EMBL:PSJ06656.1, ECO:0000313|Proteomes:UP000243002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tous {ECO:0000313|EMBL:PSJ06656.1,
RC ECO:0000313|Proteomes:UP000243002};
RX PubMed=30117250; DOI=.1111/1462-2920.14377;
RA Cabello-Yeves P.J., Picazo A., Camacho A., Callieri C., Rosselli R.,
RA Roda-Garcia J.J., Coutinho F.H., Rodriguez-Valera F.;
RT "Ecological and genomic features of two widespread freshwater
RT picocyanobacteria.";
RL Environ. Microbiol. 20:3757-3771(2018).
CC -!- FUNCTION: Methyltransferase required for the conversion of 2-
CC phytyl-1,4-beta-naphthoquinol to phylloquinol. {ECO:0000256|HAMAP-
CC Rule:MF_01982}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01982};
CC -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01982}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. MenG/UbiE family. {ECO:0000256|HAMAP-Rule:MF_01982}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSJ06656.1}.
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DR EMBL; PXXO01000003; PSJ06656.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7MZK5; -.
DR OrthoDB; 9808140at2; -.
DR UniPathway; UPA00995; -.
DR Proteomes; UP000243002; Unassembled WGS sequence.
DR GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR InterPro; IPR032904; MenG.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR NCBIfam; TIGR01934; MenG_MenH_UbiE; 1.
DR PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43591:SF106; METHYLTRANSFERASE-LIKE PROTEIN 27; 1.
DR Pfam; PF01209; Ubie_methyltran; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51608; SAM_MT_UBIE; 1.
DR PROSITE; PS01183; UBIE_1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|HAMAP-
KW Rule:MF_01982}; Reference proteome {ECO:0000313|Proteomes:UP000243002};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP-
KW Rule:MF_01982};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_01982}.
SQ SEQUENCE 234 AA; 25281 MW; 7B402DA69097661A CRC64;
MASFRPGDPQ AVQELFEQIA PRYDQLNDLL SFGLHRLWKR QAIAWLQPQP GQHLLDLCCG
TGDLALVLAG RVRPGGSVLG IDAAAAPLAV AARRAAAQPW LAVSWQQGDA LATGLASASC
DGAVIAYGLR NLADPGTGLL ELRRLLRDGG RAAVLDFNRS SGAVESFQSF YLRRLVVPTA
ERFGIPEHYA YLEESLQRFP TGSEQQQLAR RAGFSEVRHR PLAGGLMGLL ELVA
//
