ID A0A2P7YKB4_9ASCO Unreviewed; 723 AA.
AC A0A2P7YKB4;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=C7M61_003881 {ECO:0000313|EMBL:PSK36411.1};
OS [Candida] pseudohaemulonii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=418784 {ECO:0000313|EMBL:PSK36411.1, ECO:0000313|Proteomes:UP000241107};
RN [1] {ECO:0000313|EMBL:PSK36411.1, ECO:0000313|Proteomes:UP000241107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B12108 {ECO:0000313|EMBL:PSK36411.1,
RC ECO:0000313|Proteomes:UP000241107};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida pseudohaemulonii genome assembly and annotation.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK36411.1}.
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DR EMBL; PYFQ01000011; PSK36411.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7YKB4; -.
DR STRING; 418784.A0A2P7YKB4; -.
DR EnsemblFungi; C7M61_003881_t1; PSK36411.1; C7M61_003881.
DR VEuPathDB; FungiDB:C7M61_003881; -.
DR OrthoDB; 52245at2759; -.
DR Proteomes; UP000241107; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd02961; PDI_a_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR45672; PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED; 1.
DR PANTHER; PTHR45672:SF3; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000241107};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..723
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015129576"
FT TRANSMEM 676..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..175
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 22..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 82737 MW; 695C5D470BDEA10D CRC64;
MRLSLLACVP LLASAIASPA AIKPDSEGKK SEAEKSENQD TTGEAPDANA EVKMPELLTI
ETFDEFTSKH LSFIEFFSPY CHHCQALAPK WEQTFKETVE SQQSSGIHMR QVNCVESGDL
CEREIVSYYP NLRVYVPELN AEGEHTGKAK IVDSFPRALK QNPENFKKFM KKTAAEFGDG
SGSMPSSSQL LDTDTTLKIV AGEMEEPWFI GMFSSTDEEW ESGKFSRTCM DCLRIKSDWD
RLSNLIVSST KAGHLNCKSN PALCEKLGFP ELSSDLRQSP KYAMFLPKHT GIIRFDYNRG
MDIDAMKRWI QKLALNCQYE IATAGHFEDL DLFVTEKPAK PLDISLPLDP RVALIFAFDK
KKITKEDKDI LPHLLEMVTS LPFNIRLYGS GSVKFEETLE YQSKGLVDFI RTDEDLKDVQ
YNRPLHIATT LTNKPTLYMF KENSMVPTVF QNYAPEDMRN PEKLEAWVMK NMYPLFQELT
PEYIEWYFNV KDQMNDKIVV TFVDSDKEDQ FKEILYDISL VAHEYLFLKK EYYFQLLTEE
RSAKWDRINA LKEKGAEPLE VINAMKAEVP HLFDHDDALF VYIDLKAHPG LAKYVGWDID
GEGYKPGDSI VVTKNTKYYW DRSLQGEKLT VEPAKLRPVL LHLLDTQLTK GIKISGFTRK
LAASPFTSWF RTLDSVYQHG PLGVIFLLIG FYVLYKIAMR FIRRSKIGLK GRGIIGNVTE
KHD
//
