ID A0A2P7YRD5_9ASCO Unreviewed; 708 AA.
AC A0A2P7YRD5;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Magnesium transporter ALR2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=C7M61_002460 {ECO:0000313|EMBL:PSK38527.1};
OS [Candida] pseudohaemulonii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=418784 {ECO:0000313|EMBL:PSK38527.1, ECO:0000313|Proteomes:UP000241107};
RN [1] {ECO:0000313|EMBL:PSK38527.1, ECO:0000313|Proteomes:UP000241107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B12108 {ECO:0000313|EMBL:PSK38527.1,
RC ECO:0000313|Proteomes:UP000241107};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida pseudohaemulonii genome assembly and annotation.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK38527.1}.
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DR EMBL; PYFQ01000005; PSK38527.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7YRD5; -.
DR STRING; 418784.A0A2P7YRD5; -.
DR EnsemblFungi; C7M61_002460_t1; PSK38527.1; C7M61_002460.
DR VEuPathDB; FungiDB:C7M61_002460; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000241107; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF55; MAGNESIUM TRANSPORTER ALR1-RELATED; 1.
DR Pfam; PF01544; CorA; 2.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000241107};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 605..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 163..190
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 80152 MW; 9D3DF0980B4D9970 CRC64;
MSDSESYNST SANQAVPQRP DHVLNDHRQQ RENLPPPDEE GLAASGPRRN FEIPRVRRNT
RSQSVSEAVS AEDAAYLMRR SSRHSRSSLE RQDQLNVLAR YRTNDTFGSD ANAPQFLRRD
RRPSKVSMDS DADSHASRTS QETEEDVCFP MLREHVRVNG IDFDEIEEFI KEERENAEQL
RQQANMIALN TGWDAQSSGR STGNALSGRP LSKNAAKYTP KHILSKIRTN NDLISQKAPS
IQGTTTDKGR HGSESSDSAF YEKNTPDDDE SYVVKFGGAK INEDDDVALP ERFSFFHSDN
EETVHAPDIP SLVEPGQTVQ DLFKNGDGTW WLDVTCPTDA EVKTLAKAFG IHPLTAEDIR
MQETREKVEL FRSYYFVCFH TFEPDKESED YLEPINFYIV VFKEGVLTFH FAPVPHPANV
RRRVRQLREY VDVNADWLCY AMIDDITDGF APVIMGIEYE ADAIEDSVLT AREMNFSSML
RKIGEARRKV MTLMRLLSNK ADVIKMFAKR CQDENPYGVR AYEDFSPPPK SGSESANQSD
FNQQRGKVAQ PRADIALYLG DIQDHVLTMY QNLGAYEKIF SRSHSNYLAQ LQVESFNANL
RVTEILGGVT LLGTLILPMN SVFSAFGMNV EVPGQGAAGL AWFFSIIAIS FSVVFCLLCF
VRLYLKSRER SIIKQEDEKR SIRSLGMKIK SRSRDAAKSI ISFPKGYD
//
