ID A0A2P7YU42_9ASCO Unreviewed; 124 AA.
AC A0A2P7YU42;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=13 kDa ribonucleoprotein-associated protein {ECO:0000256|ARBA:ARBA00040411, ECO:0000256|RuleBase:RU366039};
GN ORFNames=C7M61_002094 {ECO:0000313|EMBL:PSK39479.1};
OS [Candida] pseudohaemulonii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=418784 {ECO:0000313|EMBL:PSK39479.1, ECO:0000313|Proteomes:UP000241107};
RN [1] {ECO:0000313|EMBL:PSK39479.1, ECO:0000313|Proteomes:UP000241107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B12108 {ECO:0000313|EMBL:PSK39479.1,
RC ECO:0000313|Proteomes:UP000241107};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida pseudohaemulonii genome assembly and annotation.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP
CC particle, required for splicing of pre-mRNA. In association with box
CC C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and
CC site-specific 2'-O-methylation of substrate RNAs. Essential for the
CC accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.
CC {ECO:0000256|ARBA:ARBA00037456, ECO:0000256|RuleBase:RU366039}.
CC -!- SUBUNIT: Component of the U3 snoRNP particle. Binds to the C'/D and B/C
CC motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle,
CC a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA.
CC {ECO:0000256|RuleBase:RU366039}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU366039}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000256|ARBA:ARBA00007337, ECO:0000256|RuleBase:RU366039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK39479.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PYFQ01000003; PSK39479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7YU42; -.
DR STRING; 418784.A0A2P7YU42; -.
DR EnsemblFungi; C7M61_002094_t1; PSK39479.1; C7M61_002094.
DR VEuPathDB; FungiDB:C7M61_002094; -.
DR OrthoDB; 5481533at2759; -.
DR Proteomes; UP000241107; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd21104; SNU13; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004037; Ribosomal_eL8-like_CS.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR InterPro; IPR018492; Ribosomal_eL8/Nhp2.
DR PANTHER; PTHR23105:SF38; NHP2-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00883; NUCLEARHMG.
DR SUPFAM; SSF55315; L30e-like; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366039};
KW Reference proteome {ECO:0000313|Proteomes:UP000241107};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU366039};
KW RNA-binding {ECO:0000256|RuleBase:RU366039};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 17..108
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
SQ SEQUENCE 124 AA; 13396 MW; 6418124901364D2B CRC64;
MSNPKAFPLA DSALTQQILD VVSQSQNLRQ LKKGANEATK TLNRGISEFI IMAADTEPIE
ILLHLPLLCE DKNVPYVFVP SKTALGRACG VSRAVIAASV TSNDASSIKN QIYGIKDKIE
TLLI
//
